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      Conceptualization and rationale for consensus definitions of terms in major depressive disorder. Remission, recovery, relapse, and recurrence.

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          Abstract

          In 1988, the MacArthur Foundation Research Network on the Psychobiology of Depression convened a task force to examine the ways in which change points in the course of depressive illness had been described and the extent to which inconsistency in these descriptions might be impeding research on this disorder. We found considerable inconsistency across and even within research reports and concluded that research on depressive illness would be well served by greater consistency in the definition change points in the course of illness. We propose an internally consistent, empirically defined conceptual scheme for the terms remission, recovery, relapse, and recurrence. In addition, we propose tentative operational criteria for each term. Finally, we discuss ways to assess the usefulness of such operational criteria through reanalysis of existing data and the design and conduct of new experiments.

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          Author and article information

          Journal
          Arch Gen Psychiatry
          Archives of general psychiatry
          American Medical Association (AMA)
          0003-990X
          0003-990X
          Sep 1991
          : 48
          : 9
          Affiliations
          [1 ] Department of Psychiatry, University of Pittsburgh School of Medicine, PA.
          Article
          10.1001/archpsyc.1991.01810330075011
          1929776
          09603520-8170-436b-bebc-3f26b109271b
          History

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