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An improved method to correct the QT interval of the electrocardiogram for changes in heart rate
November 1989
November 1989
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Abstract
The adequacy of the Bazett formula to correct for heart rate-induced changes in the
QT interval of the electrocardiogram has been frequently questioned. In the present
study, a simple linear equation was derived, which in anesthetized dogs corrects more
adequately for changes in heart rate than the Bazett formula. Regression analysis
of experimental data yielded the following equation: QTc = QT - 0.087 (RR - 1000)
= QT - 87 (60/HR - 1). The reliability of this equation was investigated in experiments
on anesthetized dogs with different cardioactive drugs with a known mechanism of action.