Antithymocyte globulin plus post-transplant cyclophosphamide combination as graft-versus-host disease prophylaxis in haploidentical peripheral blood stem cell transplantation for hematological malignancies.

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Abstract

Post-transplant cyclophosphamide (PT-Cy) and calcineurin inhibitors used in peripheral blood haplo-identical stem cell transplantation (haploSCT) increase the risk of acute/chronic graft-versus-host disease (GVHD). Whether ATG/PT-Cy is feasible for Asian patients undergoing haploSCT is unclear, and an optimal strategy for GVHD prophylaxis is needed.

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Author and article information

Journal

Journal ID (iso-abbrev): Int J Hematol

Title: International journal of hematology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1865-3774

ISSN (Print): 0925-5710

Publication date (Electronic): Apr 2022

Volume: 115

Issue: 4

Affiliations

[1 ] Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.

[2 ] College of Medicine, China Medical University, Taichung, 404, Taiwan.

[3 ] Stem Cell Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.

[4 ] Cancer Center, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.

[5 ] Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan. supengyeh@gmail.com.

Article

Publisher Item ID: 10.1007/s12185-021-03280-x

DOI: 10.1007/s12185-021-03280-x

PubMed ID: 35226308

SO-VID: 0b6bca4f-6379-4146-b8f0-a94ac14f33cb

History

Keywords: Haploidentical PBSCT,Sirolimus,ATG

Data availability:

Keywords: Haploidentical PBSCT, Sirolimus, ATG

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