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      Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials.

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          Abstract

          Tumor necrosis factor (TNF) plays an important role in host defense and tumor growth control. Therefore, anti-TNF antibody therapies may increase the risk of serious infections and malignancies.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          May 17 2006
          : 295
          : 19
          Affiliations
          [1 ] Division of Rheumatology and Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA. bongartz.tim@mayo.edu
          Article
          295/19/2275
          10.1001/jama.295.19.2275
          16705109
          0be8802b-8756-4aa0-bd49-af3f2bdac1b4
          History

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