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      High-Risk Adult Wilms' Tumour in Pregnancy: A Case Report

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          Abstract

          Wilms' tumour is the most common renal neoplasm in children with an incidence of 10 cases per 1 million children and a median age at diagnosis of 3.5 years. In Western countries its occurrence in adults is 0.2 cases per million people in western countries and carries a poorer prognosis. The co-existence of Adult Wilms' tumour and pregnancy is extremely rare with less than 20 cases published in the English literature. We present a case of a Malawian woman who had progressive high-risk metastatic Adult Wilms' tumour in pregnancy after nephrectomy, radiotherapy and two lines of chemotherapy.

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          Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients

          Roman. G. Shmakov, Frédéric Amant, Magali Verheecke … (2018)
          Awareness is growing that cancer can be treated during pregnancy, but the effect of this change on maternal and neonatal outcomes is unknown. The International Network on Cancer, Infertility and Pregnancy (INCIP) registers the incidence and maternal, obstetric, oncological, and neonatal outcomes of cancer occurring during pregnancy. We aimed to describe the oncological management and obstetric and neonatal outcomes of patients registered in INCIP and treated in the past 20 years, and assess associations between cancer type or treatment modality and obstetric and neonatal outcomes.
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            The burden of psychosocial morbidity related to cancer: patient and family issues.

            Mara Giulia Nanni, Luigi Grassi, Silvana Sabato … (2017)
            With cancer incidence increasing over time, attention to the burden of related psychiatric and psychosocial consequences of the disease and treatment is a major topic for both cancer patients and their caregivers. Among cancer patients, psychiatric (e.g. adjustment, anxiety, depressive disorders) and neuropsychiatric disorders (e.g. cognitive disorders secondary to treatment, delirium) have been shown to affect an average of 30-35% patients, with differences according to stage and type of cancer. Also other psychosocial syndromes (e.g. demoralization, health anxiety, irritable mood) not taken into account in usual nosological systems should be considered for their impact on the patient's quality-of-life. Also, it has been repeatedly reported that psychological distress reverberates substantially throughout the nuclear family, and that a family approach is necessary in cancer care, with the caregiver-patient dyad as a unit to be the focus and direction of assessment and intervention. In this review the most significant psychosocial disorders causing burden for cancer patients and their caregivers are examined, and the main methods of assessment for more proper referral and treatment are summarized.
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              Performance Status in Patients With Cancer

              Howard West, Jill O Jin (2015)
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                Author and article information

                Journal
                Journal ID (nlm-ta): Malawi Med J
                Journal ID (iso-abbrev): Malawi Med J
                Title: Malawi Medical Journal
                Publisher: The Medical Association Of Malawi (Malawi )
                ISSN (Print): 1995-7262
                ISSN (Electronic): 1995-7270
                Publication date (Print): June 2019
                Volume: 31
                Issue: 2
                Pages: 155-158
                Affiliations
                [1 ] Blantyre District Health Office, Blantyre, Malawi
                [2 ] Department of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi
                [3 ] Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
                [4 ] Department of Obstetrics and Gynaecology Department, University of Malawi College of Medicine, Blantyre, Malawi
                [5 ] Department of Obstetrics and Gynaecology, Queen Elizabeth Central Hospital, Blantyre, Malawi
                Author notes
                Correspondence: Stephen Kasenda kasendas00@ 123456gmail.com
                Article
                DOI: 10.4314/mmj.v31i2.9
                PMC ID: 6698624
                SO-VID: 0f3c70a7-39ad-44f5-9d1d-c3b4baa87539
                Copyright © © 2019 The College of Medicine and the Medical Association of Malawi.
                License:

                This work is licensed under the Creative Commons Attribution 4.0 International License. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/)

                History
                Date received : 30 July 2018
                Date revision received : 9 April 2019
                Date accepted : 19 May 2019
                Categories
                Subject: Case Report

                Keywords: africa,antineoplastic combined chemotherapy protocols,incidence,kidney,kidney neoplasms,malawi,pregnancy,wilms' tumour
                Data availability:
                Keywords: africa, antineoplastic combined chemotherapy protocols, incidence, kidney, kidney neoplasms, malawi, pregnancy, wilms' tumour

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