Changes in dorsal root ganglion CGRP expression in mouse pinch nerve injury model: Modulation by Somatostatin type-2 receptor.

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Abstract

Our previous work has shown that somatostatin effectively inhibits neuropathic pain by activating its type 2 receptor (SSTR2) in the dorsal root ganglion (DRG) and spinal cord of mice. However, the underlying mechanism of this activation has not been elucidated.

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Author and article information

Journal

Journal ID (iso-abbrev): J Chem Neuroanat

Title: Journal of chemical neuroanatomy

Publisher: Elsevier BV

ISSN (Electronic): 1873-6300

ISSN (Print): 0891-0618

Publication date (Electronic): Apr 2022

Volume: 121

Affiliations

[1 ] Institute of Medicine, Medical research center, Jishou University, Hunan, China.

[2 ] Institute of Pharmaceutical Sciences, Jishou University, Hunan, China. Electronic address: lxh_surgeon@yeah.net.

Article

Publisher Item ID: S0891-0618(22)00016-3

DOI: 10.1016/j.jchemneu.2022.102086

PubMed ID: 35257878

SO-VID: 0faa389b-dd38-4f97-ac86-2a969426fc44

History

Keywords: CGRP expression,SSTR2,Pinch nerve injury,DRG

Data availability:

Keywords: CGRP expression, SSTR2, Pinch nerve injury, DRG

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