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Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients.
Stephen E Gwilym
1 ,
John R Keltner ,
Catherine E Warnaby ,
Andrew J Carr ,
Boris Chizh ,
Iain Chessell ,
Irene Tracey
Sep 15 2009
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Abstract
The groin pain experienced by patients with hip osteoarthritis (OA) is often accompanied by areas of referred pain and changes in skin sensitivity. We aimed to identify the supraspinal influences that underlie these clinical manifestations that we consider indicative of possible central sensitization.