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      Cáncer renal bilateral sincrónico. Reporte de caso y revisión de literatura Translated title: Synchronous bilateral kidney cancer. Case report and review of literature

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          Abstract

          Resumen Hasta el 2018 la incidencia y mortalidad mundial de cáncer renal en ambos sexos fue de 4.5 y 1.8 respectivamente. El carcinoma de células renales (CCR) corresponde al 85% de los tumores renales (70% estirpe células claras), el CCR solo se reporta bilateralmente del 1.8 al 11%. Los métodos de tratamiento como la nefrectomía parcial preservan la función renal, con menor incidencia de enfermedad renal crónica y morbimortalidad por riesgo cardiovascular. Presentamos el caso de un paciente de sexo masculino de 57 años con CCR bilateral sincrónico, sometido a nefrectomía radical izquierda y nefrectomía parcial derecha, adecuada evolución y seguimiento cinco años libre de enfermedad.

          Translated abstract

          Abstract The 2018 worldwide incidence and mortality of kidney cancer in both sexes was 4.5 and 1.8. Renal cell carcinoma (RCC) comprises 85% of all kidney cancer (70% clear cell tumors lineage), however, bilateral RCC has been reported in 1.8 to 11%. Partial nephrectomy increases the preservation of kidney function, has a lower incidence rate of chronic kidney disease, morbidity, and mortality due to cardiovascular risk. We present the case of a 57-year-old male with clear cell synchronous bilateral renal cancer. Left radical nephrectomy and right partial nephrectomy were performed, with suitable clinical results and 5-year disease-free follow-up.

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          Most cited references17

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          EAU guidelines on renal cell carcinoma: 2014 update.

          The European Association of Urology Guideline Panel for Renal Cell Carcinoma (RCC) has prepared evidence-based guidelines and recommendations for RCC management.
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            The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters.

            The International Society of Urological Pathology 2012 Consensus Conference made recommendations regarding classification, prognostic factors, staging, and immunohistochemical and molecular assessment of adult renal tumors. Issues relating to prognostic factors were coordinated by a workgroup who identified tumor morphotype, sarcomatoid/rhabdoid differentiation, tumor necrosis, grading, and microvascular invasion as potential prognostic parameters. There was consensus that the main morphotypes of renal cell carcinoma (RCC) were of prognostic significance, that subtyping of papillary RCC (types 1 and 2) provided additional prognostic information, and that clear cell tubulopapillary RCC was associated with a more favorable outcome. For tumors showing sarcomatoid or rhabdoid differentiation, there was consensus that a minimum proportion of tumor was not required for diagnostic purposes. It was also agreed upon that the underlying subtype of carcinoma should be reported. For sarcomatoid carcinoma, it was further agreed upon that if the underlying carcinoma subtype was absent the tumor should be classified as a grade 4 unclassified carcinoma with a sarcomatoid component. Tumor necrosis was considered to have prognostic significance, with assessment based on macroscopic and microscopic examination of the tumor. It was recommended that for clear cell RCC the amount of necrosis should be quantified. There was consensus that nucleolar prominence defined grades 1 to 3 of clear cell and papillary RCCs, whereas extreme nuclear pleomorphism or sarcomatoid and/or rhabdoid differentiation defined grade 4 tumors. It was agreed upon that chromophobe RCC should not be graded. There was consensus that microvascular invasion should not be included as a staging criterion for RCC.
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              Partial Nephrectomy Versus Radical Nephrectomy for Clinical T1b and T2 Renal Tumors: A Systematic Review and Meta-analysis of Comparative Studies

              Partial nephrectomy (PN) is the reference standard of management for a cT1a renal mass. However, its role in the management of larger tumors (cT1b and cT2) is still under scrutiny.
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                Author and article information

                Journal
                gamo
                Gaceta mexicana de oncología
                Gac. mex. oncol.
                Sociedad Mexicana de Oncología A.C. (Ciudad de México, Ciudad de México, Mexico )
                1665-9201
                2565-005X
                2021
                : 20
                : suppl 1
                : 11-16
                Affiliations
                [2] San Bartolo Coyotepec Oax orgnameSecretaría de Salud orgdiv1Hospital Regional de Alta Especialidad de Oaxaca orgdiv2Departamento de Oncología Quirúrgica México
                [3] San Bartolo Coyotepec Oax orgnameSecretaría de Salud orgdiv1Hospital Regional de Alta Especialidad de Oaxaca orgdiv2Departamento de Anatomía Patológica México
                [1] San Bartolo Coyotepec Oax orgnameSecretaría de Salud orgdiv1Hospital Regional de Alta Especialidad de Oaxaca orgdiv2Departamento de Cirugía General y Mínima invasión México
                Article
                S2565-005X2021000500011 S2565-005X(21)02000000011
                10.24875/j.gamo.20000062
                1215b40d-0e43-4669-91bd-ad0eba592299

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 05 May 2020
                : 24 April 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 17, Pages: 6
                Product

                SciELO Mexico

                Categories
                Casos clínicos

                Conservative surgery,Renal cell cancer,Bilateral kidney tumor,Synchronous kidney cancer,Partial nephrectomy,Cáncer de células renales,Tumor renal bilateral,Tumor renal sincrónico,Cirugía conservadora,Nefrectomía parcial

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