Therapeutic Trials in Lupus Nephritis

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Abstract

Approaches to treatment of lupus nephritis have been complicated by controversies in the definitions of the types of renal histology, the relevance of immunological and renal monitoring techniques as therapeutic guidelines, and lack of definitive clinical trials. It is suggested that demonstration of the efficacy of various therapeutic agents in clinical trials may be identified earlier by renal histological changes and/or assessment of drug toxicity compared to the time required for differences based on renal functional changes to emerge as ultimate measures of outcome.

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Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1981

Publication date (Print): 1981

Publication date (Electronic): 02 December 2008

Volume: 27

Issue: 4-5

Pages: 171-176

Affiliations

Clinical Nephrology Service, Arthritis and Rheumatism Branch, NIAMDD, NIH, Bethesda, Md., USA

Article

Publisher ID: 182050 Other ID: Nephron 1981;27:171–176

DOI: 10.1159/000182050

PubMed ID: 7022237

SO-VID: 126f5b85-f8b5-499d-b6c8-1dcc99b20221

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Therapeutic Trials in Lupus Nephritis

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Abstract

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Karger: Nephrology

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