For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
31
views
165
references
 Top references
cited by
90
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      267
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds

      review-article
      Author(s): 1 , 2 , 3 , 4 , 5 , 6 , 5 , 7 , 7 , 7 , 8 , 9 , 5 , 10 , 5 , 5 , 11 , 12 , * , 13 , 14 , * , 15 , *
      Publication date (Electronic):
      Journal: International Journal of Environmental Research and Public Health
      Publisher: MDPI
      Keywords: food, diet, lifestyle, classical and emerging risk factors, atherosclerosis, arterial hypertension, diabetes, coronary artery disease, plant-food bioactive compounds, cardio-protective pharmacotherapy

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumption of plant-food bioactive derivatives including polyphenolic compounds, peptides, oligosaccharides, vitamins, unsaturated fatty acids possess protective effects on cardiovascular diseases. This review aims to summarize the cardiovascular risk factors, pre-clinical studies and clinical trials related to cardioprotective properties of the plant-food-derived bioactive compounds. Molecular mechanisms by the natural bioactive compounds exert their cardiovascular protective properties have also been highlighted.

          Related collections

          Most cited references165

          • Record: found
          • Abstract: not found
          • Article: not found

          Chemical studies of anthocyanins: A review

          Araceli Castañeda-Ovando, Ma Pacheco-Hernández, Ma. Páez-Hernández … (2009)
          Article 0 comments Cited 448 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Dietary polyphenols, oxidative stress and antioxidant and anti-inflammatory effects

            Rong Tsao, Hua Zhang (2016)
            Article 0 comments Cited 376 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

              Mary Crowell, C M McCay, L Maynard (1935)
              Article 0 comments Cited 201 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Int J Environ Res Public Health
                Journal ID (iso-abbrev): Int J Environ Res Public Health
                Journal ID (publisher-id): ijerph
                Title: International Journal of Environmental Research and Public Health
                Publisher: MDPI
                ISSN (Print): 1661-7827
                ISSN (Electronic): 1660-4601
                Publication date (Electronic): 30 March 2020
                Publication date (Print): April 2020
                Volume: 17
                Issue: 7
                Electronic Location Identifier: 2326
                Affiliations
                [1 ]Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran; javad.sharifirad@ 123456gmail.com
                [2 ]LEPABE—Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal; c.fortunae@ 123456gmail.com
                [3 ]Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, 734003 Dushanbe, Tajikistan; shfarukh@ 123456mail.ru
                [4 ]Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania; daoana00@ 123456gmail.com
                [5 ]Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, Turkey; cankaraca@ 123456itu.edu.tr (A.C.K.); kahvecid@ 123456itu.edu.tr (D.K.K.); ozcelik@ 123456itu.edu.tr (B.O.); kasapogluk@ 123456itu.edu.tr (K.N.K.); gultekinmi@ 123456itu.edu.tr (M.G.-Ö.)
                [6 ]Department of Medical Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran; mehdi_sharifirad@ 123456yahoo.com
                [7 ]Department of Food Engineering, Chemical and Metallurgical Faculty, Istanbul Technical University, Maslak Istanbul 34469, Turkey; gulsereng@ 123456itu.edu.tr (G.G.); esenol@ 123456firat.edu.tr (E.Ş.); evrendemircan@ 123456itu.edu.tr (E.D.)
                [8 ]Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran; taaheri.yasaman@ 123456gmail.com
                [9 ]Department of Agriculture and Food Systems, The University of Melbourne, Melbourne 3010, Australia; hafiz.suleria@ 123456unimelb.edu.au
                [10 ]Bioactive Research & Innovation Food Manufac. Indust. Trade Ltd., Katar Street, Teknokent ARI-3, B110, Sarıyer, Istanbul 34467, Turkey
                [11 ]Pladis TR R&D Department, Kısıklı mah., Ferah cad. Üsküdar İstanbul 34692, Turkey; ceren.dikmen@ 123456pladisglobal.com
                [12 ]Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, China
                [13 ]Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal
                [14 ]Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal
                [15 ]Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
                Author notes
                Author information
                https://orcid.org/0000-0002-7301-8151
                https://orcid.org/0000-0001-8633-2230
                https://orcid.org/0000-0003-0378-8887
                https://orcid.org/0000-0002-4137-0644
                https://orcid.org/0000-0002-1810-8154
                https://orcid.org/0000-0002-0836-236X
                https://orcid.org/0000-0002-2450-0830
                https://orcid.org/0000-0001-6070-4948
                https://orcid.org/0000-0003-4174-4586
                https://orcid.org/0000-0002-5934-5201
                https://orcid.org/0000-0002-1523-9116
                Article
                Publisher ID: ijerph-17-02326
                DOI: 10.3390/ijerph17072326
                PMC ID: 7177934
                PubMed ID: 32235611
                SO-VID: 1437cb58-7052-4c01-95e8-f79c2b364c56
                Copyright © © 2020 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 07 March 2020
                Date accepted : 27 March 2020
                Categories
                Subject: Review

                ScienceOpen disciplines: Public health
                Keywords: food,diet,lifestyle,classical and emerging risk factors,atherosclerosis,arterial hypertension,diabetes,coronary artery disease,plant-food bioactive compounds,cardio-protective pharmacotherapy
                Data availability:
                ScienceOpen disciplines: Public health
                Keywords: food, diet, lifestyle, classical and emerging risk factors, atherosclerosis, arterial hypertension, diabetes, coronary artery disease, plant-food bioactive compounds, cardio-protective pharmacotherapy

                Comments

                Comment on this article

                scite_

                Similar content267

                See all similar

                Cited by81

                See all cited by

                Most referenced authors5,442

                See all reference authors