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      An Open-source Toolbox for Analysing and Processing PhysioNet Databases in MATLAB and Octave

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          Abstract

          The WaveForm DataBase (WFDB) Toolbox for MATLAB/Octave enables integrated access to PhysioNet’s software and databases. Using the WFDB Toolbox for MATLAB/Octave, users have access to over 50 physiological databases in PhysioNet. The toolbox provides access over 4 TB of biomedical signals including ECG, EEG, EMG, and PLETH. Additionally, most signals are accompanied by metadata such as medical annotations of clinical events: arrhythmias, sleep stages, seizures, hypotensive episodes, etc. Users of this toolbox should easily be able to reproduce, validate, and compare results published based on PhysioNet’s software and databases.

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          Multiscale entropy analysis of complex physiologic time series.

          There has been considerable interest in quantifying the complexity of physiologic time series, such as heart rate. However, traditional algorithms indicate higher complexity for certain pathologic processes associated with random outputs than for healthy dynamics exhibiting long-range correlations. This paradox may be due to the fact that conventional algorithms fail to account for the multiple time scales inherent in healthy physiologic dynamics. We introduce a method to calculate multiscale entropy (MSE) for complex time series. We find that MSE robustly separates healthy and pathologic groups and consistently yields higher values for simulated long-range correlated noise compared to uncorrelated noise.
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            Derivation of respiratory signals from multi-lead ECGs.

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              An Open-source Algorithm to Detect Onset of Arterial Blood Pressure Pulses

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                Author and article information

                Journal
                101642258
                43076
                J Open Res Softw
                J Open Res Softw
                Journal of open research software
                2049-9647
                26 October 2015
                24 September 2014
                2014
                30 October 2015
                : 2
                : 1
                : e27
                Affiliations
                [1 ]Laboratory for Computational Physiology/PhysioNet, Institute for Medical Engineering and Science, Harvard-MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, USA
                Article
                NIHMS732709
                10.5334/jors.bi
                4627662
                26525081
                197beda9-56a1-4743-b227-1a4b6826e560

                This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (CC-BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/3.0/.

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                ecg,qrs,eeg,arrhythmia,physionet,biosignal processing,biomedical,database,octave,matlab,physiological signals

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