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      Computational imaging without a computer: seeing through random diffusers at the speed of light

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          Abstract

          Imaging through diffusers presents a challenging problem with various digital image reconstruction solutions demonstrated to date using computers. Here, we present a computer-free, all-optical image reconstruction method to see through random diffusers at the speed of light. Using deep learning, a set of transmissive diffractive surfaces are trained to all-optically reconstruct images of arbitrary objects that are completely covered by unknown, random phase diffusers. After the training stage, which is a one-time effort, the resulting diffractive surfaces are fabricated and form a passive optical network that is physically positioned between the unknown object and the image plane to all-optically reconstruct the object pattern through an unknown, new phase diffuser. We experimentally demonstrated this concept using coherent THz illumination and all-optically reconstructed objects distorted by unknown, random diffusers, never used during training. Unlike digital methods, all-optical diffractive reconstructions do not require power except for the illumination light. This diffractive solution to see through diffusers can be extended to other wavelengths, and might fuel various applications in biomedical imaging, astronomy, atmospheric sciences, oceanography, security, robotics, autonomous vehicles, among many others.

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          Going deeper than microscopy: the optical imaging frontier in biology.

          Optical microscopy has been a fundamental tool of biological discovery for more than three centuries, but its in vivo tissue imaging ability has been restricted by light scattering to superficial investigations, even when confocal or multiphoton methods are used. Recent advances in optical and optoacoustic (photoacoustic) imaging now allow imaging at depths and resolutions unprecedented for optical methods. These abilities are increasingly important to understand the dynamic interactions of cellular processes at different systems levels, a major challenge of postgenome biology. This Review discusses promising photonic methods that have the ability to visualize cellular and subcellular components in tissues across different penetration scales. The methods are classified into microscopic, mesoscopic and macroscopic approaches, according to the tissue depth at which they operate. Key characteristics associated with different imaging implementations are described and the potential of these technologies in biological applications is discussed.
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            Deep learning with coherent nanophotonic circuits

            Programmable silicon nanophotonic processor empowers optical neural networks.
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              Controlling waves in space and time for imaging and focusing in complex media

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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                eLight
                eLight
                Springer Science and Business Media LLC
                2662-8643
                December 2022
                January 26 2022
                December 2022
                : 2
                : 1
                Article
                10.1186/s43593-022-00012-4
                1a5edb76-0c36-4472-b1fd-cee643794b73
                © 2022

                https://creativecommons.org/licenses/by/4.0

                https://creativecommons.org/licenses/by/4.0

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