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      Comprehensive analysis of promoter methylation and altered expression of hMLH1 in gastric cancer cell lines with microsatellite instability.

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          Abstract

          Aberrant methylation of the promoter CpG island of hMLH1 is associated with gene silencing in colon cancer and gastric cancer with microsatellite instabilities (MSI). We analyzed the pattern of promoter methylation causing gene silencing.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J. Cancer Res. Clin. Oncol.
          Title: Journal of cancer research and clinical oncology
          Publisher: Springer Nature America, Inc
          ISSN: 0171-5216
          ISSN (Print): 0171-5216
          Publication date (Electronic): Mar 2002
          Volume: 128
          Issue: 3
          Affiliations
          [1 ] Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea.
          Article
          DOI: 10.1007/s00432-001-0296-z
          PubMed ID: 11935297
          SO-VID: 1d9ec3d3-0c5d-4ba1-bce7-277543010ad2
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