The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline.

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Abstract

The German COPD cohort study COSYCONET ("COPD and SYstemic consequences-COmorbidities NETwork") investigates the interaction of lung disease, comorbidities and systemic inflammation. Recruitment took place from 2010 to 2013 in 31 study centers. In addition to the baseline visit, follow-up visits are scheduled at 6, 18, 36 and 54 months after baseline. The study also comprises a biobank, image bank, and includes health economic data. Here we describe the study design of COSYCONET and present baseline data of our COPD cohort.

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Author and article information

Journal

Journal ID (iso-abbrev): Respir Med

Title: Respiratory medicine

ISSN (Electronic): 1532-3064

ISSN (Print): 0954-6111

Publication date (Electronic): May 2016

Volume: 114

Affiliations

[1 ] Institute for Biostatistics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

[2 ] Department of Respiratory Medicine, University of Marburg, University Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Baldingerstraße, 35043 Marburg, Germany.

[3 ] Clinic for Pneumology, Hannover Medical School, Member of the German Center for Lung Research, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

[4 ] Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital, Kirrberger Straße 1, 66424 Homburg, Germany.

[5 ] Department of Diagnostic and Interventional Radiology, University of Heidelberg, Translational Lung Research Center (TLRC), Member of the German Center for Lung Research, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.

[6 ] Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich (CPC-M), Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany.

[7 ] Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Scientific Division of Pneumology and Pneumological Epidemiology, Ferdinand-Sauerbruch-Strasse, 17475 Greifswald, Germany.

[8 ] Institute of Health Economics and Health Care Management, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich (CPC-M), Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany.

[9 ] LungenClinic Grosshansdorf, Pulmonary Research Institute, Airway Research Center North, Member of the German Center for Lung Research, Woehrendamm 80, 22927 Grosshansdorf, Germany.

[10 ] Pulmonary Department, Mainz University Hospital, Langenbeckstrasse 1, 55131 Mainz, Germany.

[11 ] Centre for Respiratory Medicine and Allergy, Institute for Inflammation and Repair, University of Manchester, Southmoor Rd, Manchester M23 9LT, UK.

[12 ] Department of Respiratory Medicine, Maastricht University Medical Center, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands.

[13 ] ASCONET Study Coordination Office, University of Marburg, Baldingerstraße, 35043 Marburg, Germany.

[14 ] Institute for Biostatistics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. Electronic address: koch.armin@mh-hannover.de.

[15 ] Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität München, Ziemssenstr. 1, 80336 Munich, Germany. Electronic address: rudolf.joerres@med.uni-muenchen.de.

Article

Publisher Item ID: S0954-6111(16)30038-5

DOI: 10.1016/j.rmed.2016.03.008

PubMed ID: 27109808

SO-VID: 1dd734c1-8f82-436c-8717-f47a0ba79fdd

History

Keywords: COPD,Cohort,Comorbidity,Study design,Systemic inflammation

Data availability:

Keywords: COPD, Cohort, Comorbidity, Study design, Systemic inflammation

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