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      Gender and Age-Related Differences in Bilateral Lower Extremity Mechanics during Treadmill Running

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          Abstract

          Female runners have a two-fold risk of sustaining certain running-related injuries as compared to their male counterparts. Thus, a comprehensive understanding of the sex-related differences in running kinematics is necessary. However, previous studies have either used discrete time point variables and inferential statistics and/or relatively small subject numbers. Therefore, the first purpose of this study was to use a principal component analysis (PCA) method along with a support vector machine (SVM) classifier to examine the differences in running gait kinematics between female and male runners across a large sample of the running population as well as between two age-specific sub-groups. Bilateral 3-dimensional lower extremity gait kinematic data were collected during treadmill running. Data were analysed on the complete sample ( n = 483: female 263, male 220), a younger subject group ( n = 56), and an older subject group ( n = 51). The PC scores were first sorted by the percentage of variance explained and we also employed a novel approach wherein PCs were sorted based on between-gender statistical effect sizes. An SVM was used to determine if the sex and age conditions were separable and classifiable based on the PCA. Forty PCs explained 84.74% of the variance in the data and an SVM classification accuracy of 86.34% was found between female and male runners. Classification accuracies between genders for younger subjects were higher than a subgroup of older runners. The observed interactions between age and gender suggest these factors must be considered together when trying to create homogenous sub-groups for research purposes.

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          A retrospective case-control analysis of 2002 running injuries.

          To provide an extensive and up to date database for specific running related injuries, across the sexes, as seen at a primary care sports medicine facility, and to assess the relative risk for individual injuries based on investigation of selected risk factors. Patient data were recorded by doctors at the Allan McGavin Sports Medicine Centre over a two year period. They included assessment of anthropometric, training, and biomechanical information. A model was constructed (with odds ratios and their 95% confidence intervals) of possible contributing factors using a dependent variable of runners with a specific injury and comparing them with a control group of runners who experienced a different injury. Variables included in the model were: height, weight, body mass index, age, activity history, weekly activity, history of injury, and calibre of runner. Most of the study group were women (54%). Some injuries occurred with a significantly higher frequency in one sex. Being less than 34 years old was reported as a risk factor across the sexes for patellofemoral pain syndrome, and in men for iliotibial band friction syndrome, patellar tendinopathy, and tibial stress syndrome. Being active for less than 8.5 years was positively associated with injury in both sexes for tibial stress syndrome; and women with a body mass index less than 21 kg/m(2) were at a significantly higher risk for tibial stress fractures and spinal injuries. Patellofemoral pain syndrome was the most common injury, followed by iliotibial band friction syndrome, plantar fasciitis, meniscal injuries of the knee, and tibial stress syndrome. Although various risk factors were shown to be positively associated with a risk for, or protection from, specific injuries, future research should include a non-injured control group and a more precise measure of weekly running distance and running experience to validate these results.
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            Toward a better understanding of gait changes with age and disablement: neuromuscular adaptation.

            Gait changes in the elderly, such as reduced step length and walking speed, are well documented but not well understood. This review explores the hypothesis that neuromuscular adaptations are a response to age-related impairments and play a key role in causing gait changes in the elderly, and that different neuromuscular adaptations may exist depending on the impairment and presence of comorbidities, such as knee arthritis.
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              Comparison of methods for kinematic identification of footstrike and toe-off during overground and treadmill running.

              When analysing gait, the identification of the period of stance is often needed. Forceplates are typically used, but in their absence kinematic data can be employed. Five kinematic methods have been previously described in the literature. However, these methods have not been compared to each other for overground or treadmill running. Therefore, the purpose of this study was to compare these five kinematic methods of identifying the stance phase with vertical ground reaction force data both during overground and treadmill running. We recruited forty recreational runners (20 males) for this study. Twenty runners underwent an instrumented gait analysis during overground running, and twenty were tested during instrumented treadmill running. All runners ran at 3.35 m/s. Each kinematic method was compared with stance identified from the vertical ground reaction force (gold standard) for overground running. This method was then repeated for treadmill running. Two methods were found to be valid and reliable for determining footstrike. These were the time when the distal heel marker reached a minimum vertical position, and when the vertical velocity of this same marker changed from negative to positive. These methods had absolute errors that ranged from 22.4 ms to 24.6 ms for both modes of running. Toe-off was best identified using peak knee extension, with absolute errors of 4.9 ms for overground running and 5.2 ms for treadmill running. Utilising automated kinematic methods of determining stance will aid researchers studying running when forceplates are unavailable. Copyright © 2010 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, USA )
                1932-6203
                2014
                19 August 2014
                : 9
                : 8
                : e105246
                Affiliations
                [1 ]Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada
                [2 ]Faculty of Nursing, University of Calgary, Calgary, Alberta, Canada
                [3 ]Running Injury Clinic, Calgary, Alberta, Canada
                Delft University of Technology (TUDelft), Netherlands
                Author notes

                Competing Interests: There is no commercial relationship which may lead to a conflict of interest or that could inappropriately influence (bias) this work. There is no financial affiliation (including research funding) or involvement with any commercial organization that has a direct financial interest in any matter included in this manuscript. While the authors' lab does receive funding from a commercial source (SOLE, Inc.), this relationship does not alter or influence the authors' adherence to PLOS ONE policies on sharing data and materials, and there are no competing interests. Specifically, the donation from SOLE, Inc. is for the opportunity to conduct research on foot-orthotic devices and has nothing to do with the current work.

                Conceived and designed the experiments: AP BAH SO RF. Performed the experiments: BAH SO RF. Analyzed the data: AP BAH SO RF. Contributed reagents/materials/analysis tools: AP BAH SO RF. Contributed to the writing of the manuscript: AP BAH SO RF.

                Article
                PONE-D-14-11060
                10.1371/journal.pone.0105246
                4138160
                25137240
                1e1de6b5-ae2d-4455-95c3-b9abafb728e5
                Copyright @ 2014

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 12 March 2014
                : 23 July 2014
                Page count
                Pages: 10
                Funding
                This work was supported in part by research grants from the Alberta Innovates: Health Solutions (funded by the Alberta Heritage Foundation for Medical Research endowment fund), a charitable donation from SOLE, Inc., and the University of Calgary Eyes High Postdoctoral Research Award program. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Biology and Life Sciences
                Biomechanics
                Biological Locomotion
                Gait Analysis
                Running
                Musculoskeletal Mechanics
                Neuroscience
                Cognitive Science
                Artificial Intelligence
                Machine Learning
                Support Vector Machines
                Physical Sciences
                Physics
                Classical Mechanics
                Kinematics
                Custom metadata
                The authors confirm that all data underlying the findings are fully available without restriction. All PCA data are available from the Running Injury Clinic and University of Calgary Institutional Data Access / Ethics Committee (CHREB) by contacting the corresponding author and Dr. Stacey A. Page, chair of CHREB at omb@ 123456ucalgary.ca .

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                Uncategorized

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