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      Making sense of it all: bacterial chemotaxis.

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          Abstract

          Bacteria must be able to respond to a changing environment, and one way to respond is to move. The transduction of sensory signals alters the concentration of small phosphorylated response regulators that bind to the rotary flagellar motor and cause switching. This simple pathway has provided a paradigm for sensory systems in general. However, the increasing number of sequenced bacterial genomes shows that although the central sensory mechanism seems to be common to all bacteria, there is added complexity in a wide range of species.

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          Author and article information

          Journal
          Nat Rev Mol Cell Biol
          Nature reviews. Molecular cell biology
          Springer Science and Business Media LLC
          1471-0072
          1471-0072
          Dec 2004
          : 5
          : 12
          Affiliations
          [1 ] Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
          Article
          nrm1524
          10.1038/nrm1524
          15573139
          1eaff15d-2684-45e5-9c2e-20280765ee90
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