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Tree-based linkage and association analyses of asthma.

Genetic Epidemiology

United States, Adult, African Continental Ancestry Group, genetics, Asthma, epidemiology, ethnology, Child, Chromosome Mapping, statistics & numerical data, Chromosomes, Human, Pair 1, Chromosomes, Human, Pair 11, European Continental Ancestry Group, Female, Genetic Markers, Genetic Variation, Genetics, Population, Germany, Humans, Lod Score, Male, Mathematical Computing

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      Tree-based linkage analyses and association studies are introduced and applied for two data sets on asthma from Genetic Analysis Workshop 12. Consistent and strong evidence of linkage and association to markers on chromosomes 1 and 11 is revealed. Linkage to chromosome 16 in one data set and association with D6S276 in the other data set are also detected.

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