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      Heterotopic Pancreas as a Leading Point of Intussusception: A Case Report

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          Abstract

          Heterotopic pancreas (HP) is generally asymptomatic and found incidentally. It can act very rarely as a leading point for intussusception. Thus, it should be considered as a differential diagnosis of the mass lesions leading to the intestinal intussusception. Herein, we report an unusual case of HP as a cause of ileocolic intussusception.

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          The clinical significance of heterotopic pancreas in the gastrointestinal tract.

          I Macleod, Nancy King, April W. Armstrong … (1981)
          A series of 34 histologically verified cases of pancreatic heterotopia in the records of the Department of Pathology at the University of Edinburgh between 1959 and 1979 has been analysed in order to determine the clinical significance of this unusual condition. In 13 patients (38 per cent) the heterotopic pancreatic tissue was symptomatic (i.e. the symptoms regressed completely on its removal). A correlation has been established between the presence of symptoms, the size of the lesion and the extent of mucosal involvement. Clinically significant lesions are greater than 1.5 cm in maximum diameter and are adjacent to or directly involve the mucosa.
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            Heterotopic Pancreas: A Rare Cause of Ileo-Ileal Intussusception

            Ahmed Monier, Ahmed S Awad, Wojciech Szmigielski … (2014)
            Background Heterotopic pancreas is a rare developmental anomaly defined as pancreatic tissue found on ectopic sites without contiguity with the main pancreas. An isolated heterotopic pancreas as a cause of bowel intussusception is extremely rare. Case Report A case of 47-year old male with multiple episodes of melena, constipation and abdominal pain for one year duration is presented. CT eneterography revealed a large circumferential lesion involving the terminal ileum that acted as a leading point to an ileo-ileal intussusception. The resection of the lesion and related bowel segment was carried out. The histopathological examination confirmed the excised lesion as a heterotopic pancreatic tissue. Conclusions Though a rare entity, heterotopic pancreas should be considered in the differential diagnosis of bowel intussusception.
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              Isolated heterotopic pancreas causing intussusception.

              Yoko Takada, Y Yonekura, Y Kato … (2000)
              Pediatric intussusception is usually idiopathic in origin, and a pathological lesion at the leadpoint is identified in only a small proportion of cases. Meckel's diverticulum is the most common location when such a lesion is found. Heterotopic pancreas has been seen most frequently in the stomach or duodenum; however, ileal lesions are rare. In the ileum, heterotopic pancreas is usually associated with Meckel's diverticulum and may cause intestinal obstruction by intussusception. However, isolated heterotopic pancreas in the ileum is distinctly rare and usually discovered incidentally during surgery for other conditions. In a review of English language literature, there were only a few pediatric cases of isolated ileal heterotopic pancreas causing intussusception. We report three additional pediatric cases and discuss the clinical significance of this unexpected rare entity.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Iran J Pathol
                Journal ID (iso-abbrev): Iran J Pathol
                Journal ID (publisher-id): IJP
                Title: Iranian Journal of Pathology
                Publisher: Iranian Society of Pathology (Tehran, Iran )
                ISSN (Print): 1735-5303
                ISSN (Electronic): 2345-3656
                Publication date (Print): Spring 2019
                Publication date (Electronic): 10 June 2019
                Volume: 14
                Issue: 2
                Pages: 180-183
                Affiliations
                [1 ] Associate professor, Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
                [2 ] Professor, Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
                [3 ] Assistant professor, Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
                [4 ] Anatomical and clinical pathology resident, Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
                [5 ] Internal medicine resident, Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
                Author notes
                [* ]Salma Sefidbakht, Assistant professor, Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran, Email: mollazar@yahoo.com
                Article
                DOI: 10.30699/IJP.14.2.180
                PMC ID: 6679674
                SO-VID: 1fb67dc8-589d-4400-8846-a503486b61d4
                Copyright © © 2019, IRANIAN JOURNAL OF PATHOLOGY
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, ( http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 12 April 2018
                Date accepted : 28 February 2019
                Categories
                Subject: Case Report

                Keywords: intussusception,heterotopic,pancreas
                Data availability:
                Keywords: intussusception, heterotopic, pancreas

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