8
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Multiple skeletal fibroxanthomas: radiologic-pathologic correlation of 72 cases.

      Skeletal Radiology

      Adolescent, Adult, Bone Neoplasms, pathology, radiography, Child, Child, Preschool, Female, Fibroma, Humans, Male, Middle Aged, Neoplasms, Multiple Primary

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Out of a series of 900 biopsy-proven cases of skeletal "fibroxanthoma" (nonossifying fibroma, fibrous cortical defect), we studied 72 patients with more than one lesion. Age, sex, coexistent conditions such as neurofibromatosis, and histologic and radiographic appearance of the lesions were evaluated. Multiple skeletal fibroxanthomas are probably more common than previously suspected. (At least 8% of the 900 patients in our archives had multiple lesions). Only a small percentage (5%) of patients with multiple skeletal fibroxanthomas had coexistent neurofibromatosis. These lesions are histologically indistinguishable from their solitary counterparts and most commonly present in the lower extremities. Four radiographic patterns were noted: clustered lesions--usually about the knee. nonclustered lesions--in opposite ends of long bones. coalescent lesions--several lesions coalescing over time. This observation has not been previously reported. emergent lesions--lesions appearing in previously unaffected bone. Familiarity with these features may obviate biopsy.

          Related collections

          Author and article information

          Journal
          3629279

          Comments

          Comment on this article