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      Vestibular schwannoma manifesting with hemifacial spasm in a young woman: clinical considerations and tumor removal with hearing preservation. 2-Dimensional operative video

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          Abstract

          Hemifacial spasm (HFS) is a rare presentation of vestibular schwannoma. The authors present their experience with a 27-year-old woman who presented with normal hearing and HFS, which was the single neurological manifestation of an 18-mm vestibular schwannoma. In this challenging situation, the treatment goals were maximal tumor removal with preservation of hearing and facial nerve function and cure of the HFS. The authors achieved these goals, performing complete tumor removal via a retrosigmoid approach, assisted with neurophysiological monitoring and a 45°-angle QEVO endoscope. In the video, they explain the clinical, radiological, and surgical considerations and demonstrate the surgical technique.

          The video can be found here: https://stream.cadmore.media/r10.3171/2021.7.FOCVID2099

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          Most cited references6

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          Potential neurotoxic effects of polymethylmethacrylate during cranioplasty.

          Cranioplasty for the surgical correction of cranial defects is often performed using polymethyl methacrylate (PMMA), or bone cement. Immediately prior to PMMA application, a liquid monomer form (methylacrylate) and a benzoyl peroxide accelerator are mixed resulting in polymerization, an exothermic reaction during which monomer linking and subsequent formation of solid polymer occur. The potential side effects of residual methylacrylate monomer toxicity and thermal damage of neural tissue during PMMA hardening have been described in various in vitro, animal, and cadaveric studies; however, clinically documented in vivo neurotoxicity in humans attributed to either of the above two mechanisms during PMMA cranioplasty is lacking. We present a series of four patients operated for removal of cerebellopontine angle lesions and two operated for the excision of parieto-occipital tumors who sustained cranial neuropathies and encephalopathies with transient or permanent neurological deficits that could not be attributed to surgical manipulation. We hypothesize that these complications most likely occurred due to thermal damage and/or chemical toxicity from exposure to PMMA during cranioplasty. Our case series indicates that even small volumes of PMMA used for cranioplasty may cause severe side effects related to thermal damage or to exposure of neural tissue to methylacrylate monomer.
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            Cerebellopontine angle tumors causing hemifacial spasm: types, incidence, and mechanism in nine reported cases and literature review.

            Although hemifacial spasm is usually caused by vascular compression around the root exit zone of the facial nerve, it is sometimes brought on by a cerebellopontine angle tumor. We reviewed and analyzed data from past experience with hemifacial spasm induced by cerebellopontine angle tumors. Nine patients of a total 2,050, who had presented with hemifacial spasms associated with cerebellopontine angle tumors between 1986 and 2009, were reviewed. Two vestibular schwannomas, five meningiomas, and two epidermoid tumors were included in this study. Hemifacial spasm occurred on the same side of the lesion in eight patients whereas it occurred on the opposite side of the lesion in one patient. With respect to the pathogenesis of hemifacial spasms, offending vessels were found in six patients, tumor encasement of the facial nerve in one patient, hypervascular tumor compression of the facial nerve without offending vessels in one patient, and a huge tumor compressing the brain stem and, thus, contralateral facial nerve compression in one patient. Hemifacial spasm was resolved in seven patients, whereas in two patients with a vestibular schwannoma and an epidermoid tumor, it improved transiently and then recurred in a month. Each type of tumor had different characteristics with respect to the induction of hemifacial spasm; therefore, it is suggested that neurosurgeons, who are planning surgeries both for the purposes of relieving hemifacial spasm and removal of cerebellopontine angle tumor, should thoroughly prepare appropriate approaches and specific dissecting strategies according to each causative lesion.
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              Microsurgical treatment for 55 patients with hemifacial spasm due to cerebellopontine angle tumors.

              Tumor-related hemifacial spasm (HFS) has been found to be rare. During the period from October 1984 to October 2008, we treated 6,910 HFS patients using a microsurgical procedure. Of these HFS patients, 55 cases were associated with cerebellopontine angle tumors. A small craniectomy was performed in order to excise the tumor. All tumors were found to compress the root exit zone (REZ) of the facial nerve to different extents, but concomitant vascular compression of the facial nerve was observed in a majority of cases, and microvascular decompression of the facial nerve at REZ was conducted in 43 of 55 patients (78.2%) by displacing the co-compressing vasculature away from the REZ and retaining it using a Teflon pad. Intraoperative findings and postoperative pathological examinations suggested that the tumors were epidermoid cysts, meningiomas, and Schwannomas. Follow-up in 48 of 55 patients for 4-230 months after surgery showed that the clinical symptoms of HFS disappeared in 43 cases, improved in two cases, and recurred in three cases. Ten patients had sequelae associated with the operation. We concluded from this study that the majority of cases of tumor-related HFS are caused by combined tumor and vascular co-compression at the REZ, and tumor removal and microvascular decompression are required in order to relieve the symptoms.
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                Author and article information

                Journal
                Neurosurg Focus Video
                Neurosurg Focus Video
                Neurosurg Focus Video
                Neurosurgical Focus: Video
                American Association of Neurological Surgeons
                2643-5217
                October 2021
                01 October 2021
                : 5
                : 2 , Vestibular Schwannoma Surgery
                : V11
                Affiliations
                Departments of [1 ]Neurosurgery and
                [2 ]Otolaryngology–Head and Neck Surgery, Hadassah-Hebrew University Medical Center, Jerusalem; and
                [3 ]Surgical Monitoring Services Ltd., Beit Shemesh, Israel
                Author notes
                Correspondence Sergey Spektor: Hadassah-Hebrew University Medical Center, Jerusalem, Israel. sergeyspektor@ 123456gmail.com .

                INCLUDE WHEN CITING DOI: 10.3171/2021.7.FOCVID2099.

                Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this publication.

                Article
                2021.7.FOCVID2099
                10.3171/2021.7.FOCVID2099
                9551637
                36285233
                22ec5f9a-085b-4d2a-9492-894b10e59b71
                © 2021, The Authors

                This is an open access article distributed under the CC BY license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 06 October 2020
                : 23 July 2021
                Page count
                Figures: 0, Tables: 0, References: 6, Pages: 3
                Categories
                Article

                endoscopic surgery,facial nerve,hearing preservation,hemifacial spasm,vestibular schwannoma,video

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