Research updates on the pathogenesis of adolescent idiopathic scoliosis and sports intervention

Abstract

Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity that includes scoliosis in the coronal plane, imbalance in the sagittal plane, and rotation of the vertebral body in the transverse axis without any congenital spinal anomalies or combined neuromuscular and skeletal disorders, and is the most common structural scoliosis in clinical practice. Epidemiological surveys have shown that the prevalence of AIS in China is on the rise and has become another important health problem threatening the health of our youth. Studies have found that exercise therapy shows positive effects on the prevention and treatment of AIS, but the underlying mechanisms are not well understood. This paper reviewed relevant literature through China Knowledge Network (CNKI), Web of Science, PubMed, Elsevier, regarding pathological mechanisms of the occurrence and development of AIS, as well as effectiveness of exercise therapy on AIS and related mechanisms during recent years, to provide reference for the treatment of AIS.

Abstract

【摘要】 青少年特发性脊柱侧弯 (adolescent idiopathic scoliosis, AIS)指一种包括冠状面上的侧弯、矢状面上的失平衡和椎 体在横轴位上旋转在内的三维畸形, 无任何先天性脊柱异常或合并有神经肌肉和骨骼等疾病, 是临床最常见的结构性脊柱 侧弯。中国AIS的患病率呈不断上升趋势, 成为威胁青少年健康的重要卫生问题。运动疗法对于预防与治疗AIS具有积 极的效应, 但其潜在机制尚不十分明确。研究综述了近年来关于AIS发生与发展的病理机制及运动疗法对AIS的干预作 用及相关机制, 以期为治疗AIS提供参考。