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      Biosafety and Biohazards: Understanding Biosafety Levels and Meeting Safety Requirements of a Biobank

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          Abstract

          When it comes to biobanking and working with different types of laboratory specimens, it is important to understand potential biohazards to ensure safety of the operator and laboratory personnel. Biological safety levels (BSL) are a series of designations used to inform laboratory personnel about the level of biohazardous risks in a laboratory setting. There are a total of four levels ranked in order of increasing risk as stipulated by the Center of Disease Control and Prevention (CDC) (Biosafety in microbiological and biomedical laboratories, 5th edn. HHS publication no. (CDC) 21-1112. https://www.cdc.gov/biosafety/publications/bmbl5/bmbl.pdf. Accessed 2 Jan 2016, 2009). We will address the main distinctions between these levels including briefly introducing hazards characteristics that classify biohazardous agents, as well as define the essentials in meeting safety requirements.

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          Contributors
          +11310-825-8269 , +11310-825-7353 , wyong@mednet.ucla.edu
          dnathanson@mednet.ucla.edu
          Journal
          978-1-4939-8935-5
          10.1007/978-1-4939-8935-5
          Biobanking
          Biobanking
          Methods and Protocols
          978-1-4939-8933-1
          978-1-4939-8935-5
          12 December 2018
          2019
          : 1897
          : 213-225
          Affiliations
          GRID grid.19006.3e, ISNI 0000 0000 9632 6718, Division of Neuropathology, Department of Pathology and Laboratory Medicine, Brain Tumor Translational Resource, , Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, ; Los Angeles, CA USA
          [3 ]GRID grid.19006.3e, ISNI 0000 0000 9632 6718, Department of Molecular and Medical Pharmacology, , David Geffen School of Medicine at UCLA, ; Los Angeles, CA USA
          [4 ]GRID grid.19006.3e, ISNI 0000 0000 9632 6718, Ahmanson Translational Imaging Division, , David Geffen School of Medicine at UCLA, ; Los Angeles, CA USA
          Article
          19
          10.1007/978-1-4939-8935-5_19
          7120677
          30539447
          260438e2-2f06-4993-b0ad-2f47e7ca8e83
          © Springer Science+Business Media, LLC, part of Springer Nature 2019

          This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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          © Springer Science+Business Media, LLC, part of Springer Nature 2019

          biosafety,safety requirements,biohazard,biosafety levels,personal protective equipment

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