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Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma.
Naoto Fujiwara
1 ,
Hayato Nakagawa
1 ,
Yotaro Kudo
1 ,
Ryosuke Tateishi
2 ,
Masataka Taguri
3 ,
Takeyuki Watadani
4 ,
Ryo Nakagomi
1 ,
Mayuko Kondo
1 ,
Takuma Nakatsuka
1 ,
Tatsuya Minami
1 ,
Masaya Sato
1 ,
Koji Uchino
1 ,
Kenichiro Enooku
1 ,
Yuji Kondo
1 ,
Yoshinari Asaoka
1 ,
Yasuo Tanaka
1 ,
Kuni Ohtomo
4 ,
Shuichiro Shiina
5 ,
Kazuhiko Koike
1
Jul 2015
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Abstract
Obesity defined by body mass index (BMI) significantly increases the risk of hepatocellular carcinoma (HCC). In contrast, not only obesity but also underweight is associated with poor prognosis in patients with HCC. Differences in body composition rather than BMI were suggested to be true determinants of prognosis. However, this hypothesis has not been demonstrated conclusively.