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      Inequalities in Life Expectancy Among US Counties, 1980 to 2014 : Temporal Trends and Key Drivers

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          Abstract

          Importance

          Examining life expectancy by county allows for tracking geographic disparities over time and assessing factors related to these disparities. This information is potentially useful for policy makers, clinicians, and researchers seeking to reduce disparities and increase longevity.

          Objective

          To estimate annual life tables by county from 1980 to 2014; describe trends in geographic inequalities in life expectancy and age-specific risk of death; and assess the proportion of variation in life expectancy explained by variation in socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors.

          Design, Setting, and Participants

          Annual county-level life tables were constructed using small area estimation methods from deidentified death records from the National Center for Health Statistics (NCHS), and population counts from the US Census Bureau, NCHS, and the Human Mortality Database. Measures of geographic inequality in life expectancy and age-specific mortality risk were calculated. Principal component analysis and ordinary least squares regression were used to examine the county-level association between life expectancy and socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors.

          Exposures

          County of residence.

          Main Outcomes and Measures

          Life expectancy at birth and age-specific mortality risk.

          Results

          Counties were combined as needed to create stable units of analysis over the period 1980 to 2014, reducing the number of areas analyzed from 3142 to 3110. In 2014, life expectancy at birth for both sexes combined was 79.1 (95% uncertainty interval [UI], 79.0-79.1) years overall, but differed by 20.1 (95% UI, 19.1-21.3) years between the counties with the lowest and highest life expectancy. Absolute geographic inequality in life expectancy increased between 1980 and 2014. Over the same period, absolute geographic inequality in the risk of death decreased among children and adolescents, but increased among older adults. Socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors explained 60%, 74%, and 27% of county-level variation in life expectancy, respectively. Combined, these factors explained 74% of this variation. Most of the association between socioeconomic and race/ethnicity factors and life expectancy was mediated through behavioral and metabolic risk factors.

          Conclusions and Relevance

          Geographic disparities in life expectancy among US counties are large and increasing. Much of the variation in life expectancy among counties can be explained by a combination of socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors. Policy action targeting socioeconomic factors and behavioral and metabolic risk factors may help reverse the trend of increasing disparities in life expectancy in the United States.

          Abstract

          This data analysis estimates trends in geographic inequalities in life expectancy and age-specific risk of death by US county from 1980 to 2014.

          Key Points

          Question

          Are inequalities in life expectancy among counties in the United States growing or diminishing, and what factors can explain differences in life expectancy among counties?

          Findings

          In this population-based analysis, inequalities in life expectancy among counties are large and growing, and much of the variation in life expectancy can be explained by differences in socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors.

          Meaning

          Policy action targeting socioeconomic factors and behavioral and metabolic risk factors may help reverse the trend of increasing disparities in life expectancy in the United States.

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          Author and article information

          Journal
          JAMA Intern Med
          JAMA Intern Med
          JAMA Intern Med
          JAMA Internal Medicine
          American Medical Association
          2168-6106
          2168-6114
          8 May 2017
          3 July 2017
          July 2017
          3 July 2018
          : 177
          : 7
          : 1003-1011
          Affiliations
          [1 ]Institute for Health Metrics and Evaluation, University of Washington, Seattle
          [2 ]Department of Public Health, Erasmus MC, Rotterdam, Netherlands
          Author notes
          Article Information
          Corresponding Author: Christopher J. L. Murray, MD, DPhil, Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Ave, Ste 600, Seattle, WA 98121 ( cjlm@ 123456uw.edu ).
          Accepted for Publication: February 26, 2017.
          Published Online: May 8, 2017. doi:10.1001/jamainternmed.2017.0918
          Author Contributions: Dr Murray had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
          Study concept and design: Dwyer-Lindgren, Bertozzi-Villa, Mokdad, Murray.
          Acquisition, analysis, or interpretation of data: All authors.
          Drafting of the manuscript: Dwyer-Lindgren, van Lenthe.
          Critical revision of the manuscript for important intellectual content: Bertozzi-Villa, Stubbs, Morozoff, Mackenbach, van Lenthe, Mokdad, Murray.
          Statistical analysis: Dwyer-Lindgren, Bertozzi-Villa, Stubbs, van Lenthe.
          Obtained funding: Mokdad, Murray.
          Administrative, technical, or material support: Morozoff, Mokdad, Murray.
          Study supervision: Mackenbach, van Lenthe, Mokdad, Murray.
          Conflict of Interest Disclosures: None reported.
          Funding/Support: This work was funded by the Robert Wood Johnson Foundation (No. 72305), the National Institute on Aging (grant No. 5P30AG047845-02), and a philanthropic gift from John W. Stanton and Theresa E. Gillespie.
          Role of the Funder/Sponsor: The funders/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
          Article
          PMC5543324 PMC5543324 5543324 ioi170020
          10.1001/jamainternmed.2017.0918
          5543324
          28492829
          26be5dd8-f2d5-4d17-acb5-2a07511f2c91
          Copyright 2017 American Medical Association. All Rights Reserved.
          History
          : 14 December 2016
          : 21 February 2017
          : 26 February 2017
          Categories
          Research
          Research
          Original Investigation
          Health Care Policy and Law
          Online First

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