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Abstract
PurposeTo compare optical coherence tomographic angiography (OCTA) and indocyanine
green angiography (ICGA) images for detecting polypoidal lesions (PLs) and branching
vascular networks (BVNs), and to measure the polypoidal areas (PAs) in patients with
polypoidal choroidal vasculopathy (PCV).MethodsAll patients underwent ICGA, optical
coherence tomography (OCT), and OCTA. We compared the detection sensitivity for PL
and BVN, as evaluated by the ICGA and OCTA images. Furthermore, PA measured by ICGA
was divided into two groups: one in which the area could be measured by OCTA (ICGA+OCTA+)
and the other in which the area could not be measured by OCTA (ICGA+OCTA-).ResultsTwenty-one
consecutive eyes of 21 patients (mean age, 73.8±9.8 years) were included. ICGA detected
PL in all eyes (100%), whereas OCTA detected PL in 16 eyes (75.2%); ICGA detected
BVN in 15 eyes (71.4%), whereas OCTA detected BVN in 20 eyes (95.2%). The mean PA
in ICGA+OCTA+ and ICGA+OCTA- was 0.24±0.04 and 0.14±0.01 mm2, respectively; a significant
difference was observed between ICGA+OCTA+ PA and ICGA+OCTA- PA (P<0.0001). In addition,
the mean PA in the ICGA+OCTA+ group measured by ICGA and OCTA was 0.24±0.04 was 0.19±0.04 mm2,
respectively; these values were significantly different (P=0.0046).ConclusionsOCTA
might detect more BVNs and fewer PLs compared with ICGA, and PL detected by OCTA might
be smaller than those detected by ICGA.