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Tissue plasminogen activator for acute ischemic stroke.

The New England journal of medicine

New England Journal of Medicine (NEJM/MMS)

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      Abstract

      Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of intracerebral hemorrhage in early clinical trials. We performed a randomized, double-blind trial of intravenous recombinant tissue plasminogen activator (t-PA) for ischemic stroke after recent pilot studies suggested that t-PA was beneficial when treatment was begun within three hours of the onset of stroke.

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      Author and article information

      Journal
      N. Engl. J. Med.
      The New England journal of medicine
      New England Journal of Medicine (NEJM/MMS)
      0028-4793
      0028-4793
      December 14 1995
      : 333
      : 24
      7477192 10.1056/NEJM199512143332401

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