- Record: found
- Abstract: found
- Article: not found
Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: association with tumor progression.
Celine Debiais-Delpech
1 ,
Julie Godet
1 ,
Nathalie Pedretti
2 ,
François-Xavier Bernard
2 ,
Jacques Irani
3 ,
Xavier Cathelineau
4 ,
Olivier Cussenot
5 ,
Gaelle Fromont
6
May 2014
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Genome-wide association studies have identified variants at multiple loci associated with prostate cancer (PCa) risk. Some of these loci include candidate susceptibility genes, such as MSMB, HNF1β, and C-terminal-binding protein (CtBP2). Except for MSMB, the clinicopathological significance of these genes has not been investigated. We therefore aimed to analyze their expression in PCa tissues, in relation with tumor progression and aggressiveness.