Management of anemia in patients with diabetic kidney disease: A consensus statement

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Abstract

This consensus statement focuses on the window of opportunity, which exists while treating patients with diabetic kidney disease and anemia.

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Most cited references 133

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.

Sarah E Wild, Gojka Roglic, Anders Green … (2004)

The goal of this study was to estimate the prevalence of diabetes and the number of people of all ages with diabetes for years 2000 and 2030. Data on diabetes prevalence by age and sex from a limited number of countries were extrapolated to all 191 World Health Organization member states and applied to United Nations' population estimates for 2000 and 2030. Urban and rural populations were considered separately for developing countries. The prevalence of diabetes for all age-groups worldwide was estimated to be 2.8% in 2000 and 4.4% in 2030. The total number of people with diabetes is projected to rise from 171 million in 2000 to 366 million in 2030. The prevalence of diabetes is higher in men than women, but there are more women with diabetes than men. The urban population in developing countries is projected to double between 2000 and 2030. The most important demographic change to diabetes prevalence across the world appears to be the increase in the proportion of people >65 years of age. These findings indicate that the "diabetes epidemic" will continue even if levels of obesity remain constant. Given the increasing prevalence of obesity, it is likely that these figures provide an underestimate of future diabetes prevalence.

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Mechanisms of anemia in CKD.

Jodie L. Babitt, Herbert Y. Lin (2012)

Anemia is a common feature of CKD associated with poor outcomes. The current management of patients with anemia in CKD is controversial, with recent clinical trials demonstrating increased morbidity and mortality related to erythropoiesis stimulating agents. Here, we examine recent insights into the molecular mechanisms underlying anemia of CKD. These insights hold promise for the development of new diagnostic tests and therapies that directly target the pathophysiologic processes underlying this form of anemia.

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Diabetic kidney disease: a report from an ADA Consensus Conference.

Katherine Tuttle, George L. Bakris, Rudolf W. Bilous … (2014)

The incidence and prevalence of diabetes mellitus have grown significantly throughout the world, due primarily to the increase in type 2 diabetes. This overall increase in the number of people with diabetes has had a major impact on development of diabetic kidney disease (DKD), one of the most frequent complications of both types of diabetes. DKD is the leading cause of end-stage renal disease (ESRD), accounting for approximately 50% of cases in the developed world. Although incidence rates for ESRD attributable to DKD have recently stabilized, these rates continue to rise in high-risk groups such as middle-aged African Americans, Native Americans, and Hispanics. The costs of care for people with DKD are extraordinarily high. In the Medicare population alone, DKD-related expenditures among this mostly older group were nearly $25 billion in 2011. Due to the high human and societal costs, the Consensus Conference on Chronic Kidney Disease and Diabetes was convened by the American Diabetes Association in collaboration with the American Society of Nephrology and the National Kidney Foundation to appraise issues regarding patient management, highlighting current practices and new directions. Major topic areas in DKD included (1) identification and monitoring, (2) cardiovascular disease and management of dyslipidemia, (3) hypertension and use of renin-angiotensin-aldosterone system blockade and mineralocorticoid receptor blockade, (4) glycemia measurement, hypoglycemia, and drug therapies, (5) nutrition and general care in advanced-stage chronic kidney disease, (6) children and adolescents, and (7) multidisciplinary approaches and medical home models for health care delivery. This current state summary and research recommendations are designed to guide advances in care and the generation of new knowledge that will meaningfully improve life for people with DKD.

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Author and article information

Journal

Journal ID (nlm-ta): Indian J Endocrinol Metab

Journal ID (iso-abbrev): Indian J Endocrinol Metab

Journal ID (publisher-id): IJEM

Title: Indian Journal of Endocrinology and Metabolism

Publisher: Medknow Publications & Media Pvt Ltd (India )

ISSN (Print): 2230-8210

ISSN (Electronic): 2230-9500

Publication date (Print): Mar-Apr 2016

Volume: 20

Issue: 2

Pages: 268-281

Affiliations

[1 ] Director-Professor and Head, Department of Medicine, MLN Medical College, Allahabad, India

[2 ] Sr. Consultant Physician and Diabetologist, Diabetes and Obesity Centre, Paschim Vihar, New Delhi, India

[3 ] Hon. Diabetologist, Bodyline Hospitals, Paldi, Ahmedabad, India

[4 ] Hon. Diabetologist, S.L. Raheja Hospital, Mumbai, India

[5 ] Consultant Diabetologist, Dia Care - Diabetes Care and Hormone Clinic, Ambawadi, Ahmedabad, India

[6 ] Medical Director and Senior Consultant Endocrinology Diabetes, Samatvam Endocrinology Diabetes Center, Samatvam: Science and Research for Human Welfare Trust, Jnana Sanjeevini Diabetes Hospital and Medical Center, Bengaluru, India

[7 ] Professor of Medicine and Head of Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry, India

[8 ] Consultant Endocrinology, Diabetology and Metabolism, Global Hospitals, Adyar Cancer Institute, Vikas Center for Hormones and Mental Health, Chennai, India

[9 ] Consultant, Division of Internal Medicine, Medanta - The Medicity Hospital, Gurgaon, Haryana, India

[10 ] Consultant Nephrologist, Lilavati Hospital and Bharatiya Arogyanidhi Hospital, Mumbai, India

[11 ] Professor of Medicine, Pondicherry Institute of Medical Sciences, Puducherry and Consultant – Nephrologist, Madras Medical Mission, Chennai, India

[12 ] Executive Chief Editor and Editorial Head, Passi HealthCom Pvt. Ltd., Delhi, India

[13 ] Sr. Executive Editor, Passi HealthCom Pvt. Ltd, Delhi, India

Author notes

Corresponding Author: Dr. Sushil Kumar, Passi HealthCom Pvt. Ltd., Postal Address: 303-4, 17–18, Virat Bhawan, Commercial Complex, Dr. Mukherjee Nagar, New Delhi - 110 009, India. E-mail: drsushil@ 123456passi.org

Article

Publisher ID: IJEM-20-268

DOI: 10.4103/2230-8210.176348

PMC ID: 4792030

PubMed ID: 27042425

SO-VID: 2a584559-7a22-4861-98bd-eabc530df785

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Management of anemia in patients with diabetic kidney disease: A consensus statement

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Bioscientifica Open Endocrinology

Most cited references 133

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.

Mechanisms of anemia in CKD.

Diabetic kidney disease: a report from an ADA Consensus Conference.

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