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      Clinical effectiveness of chin cup treatment for the management of Class III malocclusion in pre-pubertal patients: a systematic review and meta-analysis

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          Abstract

          Background

          Chin cup is regarded as the oldest orthodontic appliance for the management of Class III malocclusion. To assess its clinical effectiveness in pre-pubertal patients, a meta-analysis on specific cephalometric values is attempted.

          Methods

          Detailed electronic and hand searches with no restrictions were performed up to July 2014. Only randomized controlled trials (RCTs) and cohort studies, i.e. prospective controlled trials (pCCTs) and (retrospective) observational studies (OS), were included. Analyses were performed by calculating the standard difference in means and the corresponding 95% confidence intervals, using the random effects model. Data heterogeneity and risk of bias assessment of the included studies were also performed. Study selection, data extraction and risk of bias assessment were performed twice. The level of significance was set at P ≤ 0.05 for all tests, except for heterogeneity ( P ≤ 0.1).

          Results

          Seven treated groups from five studies (no RCTs, four pCCTs, one OS) were eligible for inclusion, assessing only the short-term occipital pull chin cup effects. In total, 120 treated patients (mean age: 8.5 to 11 years) compared with 64 untreated individuals (mean age: 7.3 to 9.89 years) were assessed by means of 13 cephalometric variables. The overall quality of these studies was low to medium. In comparison to untreated individuals, the SNB and gonial angles decreased significantly following chin cup use, whereas ANB, Wits appraisal, SN-ML, N-Me and overjet increased. For the rest of the variables, no statistically significant differences were detected.

          Conclusions

          Although the occipital chin cup affects significantly a number of skeletal and dentoalveolar cephalometric variables, indicating an overall positive effect for the treatment of Class III malocclusion, data heterogeneity and between-studies variance impose precaution in the interpretation of the results.

          Electronic supplementary material

          The online version of this article (doi:10.1186/s40510-014-0062-9) contains supplementary material, which is available to authorized users.

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          Most cited references37

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          Failure rates and associated risk factors of orthodontic miniscrew implants: a meta-analysis.

          Risk factors concerning orthodontic miniscrew implants have not been adequately assessed. In this systematic review, we summarize the knowledge from published clinical trials regarding the failure rates of miniscrew implants used for orthodontic anchorage purposes and identify the factors that possibly affect them. Nineteen electronic databases and reference lists of included studies were searched up to February 2011, with no restrictions. Only randomized controlled trials, prospective controlled trials, and prospective cohort studies were included. Study selection and data extraction were performed twice. Failure event rates, relative risks, and the corresponding 95% confidence intervals were calculated. The random-effects model was used to assess each factor's impact. Subgroup and meta-regression analyses were also implemented. Fifty-two studies were included for the overall miniscrew implant failure rate and 30 studies for the investigation of risk factors. From the 4987 miniscrew implants used in 2281 patients, the overall failure rate was 13.5% (95% confidence interval, 11.5-15.8). Failures of miniscrew implants were not associated with patient sex or age and miniscrew implant insertion side, whereas they were significantly associated with jaw of insertion. Certain trends were identified through exploratory analysis; however, because of the small number of original studies, no definite conclusions could be drawn. Orthodontic miniscrew implants have a modest small mean failure rate, indicating their usefulness in clinical practice. Although many factors seem to affect their failure rates, the majority of them still need additional evidence to support any possible associations. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.
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            Papers that go beyond numbers (qualitative research)

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              Advances in Meta-Analysis

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                Author and article information

                Contributors
                mariachatzoudi@yahoo.gr
                ioanidou@dent.auth.gr
                mikepap@dent.auth.gr
                Journal
                Prog Orthod
                Prog Orthod
                Progress in Orthodontics
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                1723-7785
                2196-1042
                2 December 2014
                2 December 2014
                2014
                : 15
                : 1
                : 62
                Affiliations
                [ ]Komninon 75, Kalamaria 55132 Thessaloniki, Greece
                [ ]Department of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
                Article
                62
                10.1186/s40510-014-0062-9
                4250531
                25679781
                2aff2420-6c9e-43b8-87d2-d129f76548bc
                © Chatzoudi et al.; licensee Springer. 2014

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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                Research
                Custom metadata
                © The Author(s) 2014

                class iii malocclusion,class iii treatment,chin cup,systematic review,meta-analysis

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