The purpose of this article is to move beyond the vulnerability/deficit model of women and to focus on women's strengths and their ability to thrive in the face of adversity. Thriving is a dynamic process of adaptation, influenced by numerous individual and social factors; it emerges and changes over the life course and may be identified in behavioral, cognitive, or affective domains. The foundation of this concept comes from the literature on resilience, but it goes beyond the common view of resilience as homeostasis. It suggests, instead, a value-added construct whereby challenge provides an opportunity for change and growth. Understanding the concept and process of thriving can provide an important basis for theoretical development, empirical research, and clinical intervention. Thriving can provide a framework within which to examine the antecedents and consequences of differential reactions to health-related challenges. Knowledge of the factors that promote thriving can provide an important foundation for a paradigm shift away from a focus on illness and pathology toward one that understands, explains, and nurtures health.