There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

We report a case of Lemierre's syndrome due to Fusobacterium nucleatum in a previously healthy 19-year-old male. This is the first case report of Lemierre's syndrome due to thrombophlebitis of the external jugular vein. The patient had a rapid clinical response to anticoagulation and antibiotics, as supported by anecdotal evidence.

Related collections

Most cited references 31

Record: found
Abstract: found
Article: not found

The global burden of pathogens and pests on major food crops

Serge Savary, Laetitia Willocquet, Sarah Pethybridge … (2019)

Crop pathogens and pests reduce the yield and quality of agricultural production. They cause substantial economic losses and reduce food security at household, national and global levels. Quantitative, standardized information on crop losses is difficult to compile and compare across crops, agroecosystems and regions. Here, we report on an expert-based assessment of crop health, and provide numerical estimates of yield losses on an individual pathogen and pest basis for five major crops globally and in food security hotspots. Our results document losses associated with 137 pathogens and pests associated with wheat, rice, maize, potato and soybean worldwide. Our yield loss (range) estimates at a global level and per hotspot for wheat (21.5% (10.1-28.1%)), rice (30.0% (24.6-40.9%)), maize (22.5% (19.5-41.1%)), potato (17.2% (8.1-21.0%)) and soybean (21.4% (11.0-32.4%)) suggest that the highest losses are associated with food-deficit regions with fast-growing populations, and frequently with emerging or re-emerging pests and diseases. Our assessment highlights differences in impacts among crop pathogens and pests and among food security hotspots. This analysis contributes critical information to prioritize crop health management to improve the sustainability of agroecosystems in delivering services to societies.

0 comments Cited 668 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Disease Impact on Wheat Yield Potential and Prospects of Genetic Control.

Ravi Singh, Pawan K. Singh, Jessica Rutkoski … (2016)

Wheat is grown worldwide in diverse geographical regions, environments, and production systems. Although many diseases and pests are known to reduce grain yield potential and quality, the three rusts and powdery mildew fungi have historically caused major crop losses and continue to remain economically important despite the widespread use of host resistance and fungicides. The evolution and fast spread of virulent and more aggressive race lineages of rust fungi have only worsened the situation. Fusarium head blight, leaf spotting diseases, and, more recently, wheat blast (in South America and Bangladesh) have become diseases of major importance in recent years largely because of intensive production systems, the expansion of conservation agriculture, undesirable crop rotations, or increased dependency on fungicides. High genetic diversity for race-specific and quantitative resistance is known for most diseases; their selection through phenotyping reinforced with molecular strategies offers great promise in achieving more durable resistance and enhancing global wheat productivity.

0 comments Cited 148 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

A unique wheat disease resistance-like gene governs effector-triggered susceptibility to necrotrophic pathogens.

Justin Faris, Zengcui Zhang, Huangjun Lu … (2010)

Plant disease resistance is often conferred by genes with nucleotide binding site (NBS) and leucine-rich repeat (LRR) or serine/threonine protein kinase (S/TPK) domains. Much less is known about mechanisms of susceptibility, particularly to necrotrophic fungal pathogens. The pathogens that cause the diseases tan spot and Stagonospora nodorum blotch on wheat produce effectors (host-selective toxins) that induce susceptibility in wheat lines harboring corresponding toxin sensitivity genes. The effector ToxA is produced by both pathogens, and sensitivity to ToxA is governed by the Tsn1 gene on wheat chromosome arm 5BL. Here, we report the cloning of Tsn1, which was found to have disease resistance gene-like features, including S/TPK and NBS-LRR domains. Mutagenesis revealed that all three domains are required for ToxA sensitivity, and hence disease susceptibility. Tsn1 is unique to ToxA-sensitive genotypes, and insensitive genotypes are null. Sequencing and phylogenetic analysis indicated that Tsn1 arose in the B-genome diploid progenitor of polyploid wheat through a gene-fusion event that gave rise to its unique structure. Although Tsn1 is necessary to mediate ToxA recognition, yeast two-hybrid experiments suggested that the Tsn1 protein does not interact directly with ToxA. Tsn1 transcription is tightly regulated by the circadian clock and light, providing further evidence that Tsn1-ToxA interactions are associated with photosynthesis pathways. This work suggests that these necrotrophic pathogens may thrive by subverting the resistance mechanisms acquired by plants to combat other pathogens.

0 comments Cited 85 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

PubMed ID:: 12843117

PMC ID:: 165296

DOI:: 10.1128/jcm.41.7.3445-3448.2003

ScienceOpen disciplines: Chemistry

Keywords: Adult,Fusobacterium Infections,microbiology,Fusobacterium nucleatum,isolation & purification,Humans,Jugular Veins,Male,Pharyngitis,complications,Syndrome,Thrombophlebitis

Data availability:

ScienceOpen disciplines: Chemistry

Keywords: Adult, Fusobacterium Infections, microbiology, Fusobacterium nucleatum, isolation & purification, Humans, Jugular Veins, Male, Pharyngitis, complications, Syndrome, Thrombophlebitis

Unusual presentation of Lemierre's syndrome due to Fusobacterium nucleatum.

Read this article at

Abstract

Related collections

Cures Within Reach: Autoimmune Lymphoproliferative Syndrome (ALPS)

Most cited references 31

The global burden of pathogens and pests on major food crops

Disease Impact on Wheat Yield Potential and Prospects of Genetic Control.

A unique wheat disease resistance-like gene governs effector-triggered susceptibility to necrotrophic pathogens.

Author and article information

Journal

Comments

Comment on this article

Similar content 398

Cited by 19

Most referenced authors 431