Quantitative multiparametric MRI in uveal melanoma: increased tumor permeability may predict monosomy 3.

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Abstract

Uveal melanoma is a rare intraocular tumor with heterogeneous biological behavior, and additional noninvasive markers that may predict outcome are needed. Diffusion- and perfusion-weighted imaging may prove useful but have previously been limited in their ability to evaluate ocular tumors. Our purpose was to show the feasibility and potential value of a multiparametric (mp-) MRI protocol employing state of the art diffusion- and perfusion-weighted imaging techniques.

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Journal

Journal ID (iso-abbrev): Neuroradiology

Title: Neuroradiology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-1920

ISSN (Print): 0028-3940

Publication date (Electronic): Aug 2015

Volume: 57

Issue: 8

Affiliations

[1 ] Department of Radiation Oncology, University of California Los Angeles, 200 Medical Plaza, Ste B265, Los Angeles, CA, 90095, USA.

Article

DOI: 10.1007/s00234-015-1546-0

PubMed ID: 26022354

SO-VID: 2dbdd30f-bb6e-48e2-93d8-7fe2de554110

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