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      Detecting Chemical Hazards in Foods Using Microfluidic Paper-Based Analytical Devices (μPADs): The Real-World Application

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          Abstract

          Food safety remains one of the most important issues in most countries and the detection of food hazards plays a key role in the systematic approach to ensuring food safety. Rapid, easy-to-use and low-cost analytical tools are required to detect chemical hazards in foods. As a promising candidate, microfluidic paper-based analytical devices (μPADs) have been rarely applied to real food samples for testing chemical hazards, although numerous papers have been published in this field in the last decade. This review discusses the current status and concerns of the μPAD applications in the detection of chemical hazards in foods from the perspective of food scientists, mainly for an audience with a background in mechanical and chemical engineering who may have interests in exploring the potential of μPAD to address real-world food safety issues.

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          Most cited references46

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          Paper-Based Microfluidic Devices: Emerging Themes and Applications.

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            Bioactive paper provides a low-cost platform for diagnostics

            Bioactive paper includes a range of potential paper-based materials that can perform analytical functions normally reserved for multi-well plates in the laboratory or for portable electronic devices. Pathogen detection is the most compelling application. Simple paper-based detection, not requiring hardware, has the potential to have impacts in society, ranging from the kitchen to disasters in the developing world. Bioactive-paper research is an emerging field with significant efforts in Canada, USA (Harvard), Finland and Australia. Following a brief introduction to the material and surface properties of paper, I review the literature. Some of the early work exploits the porosity of paper to generate paper-based microfluidics (“paperfluidics”) devices. I exclude from this review printed electronic devices and plastics-supported devices.
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              Review on microfluidic paper-based analytical devices towards commercialisation

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                Author and article information

                Journal
                Micromachines (Basel)
                Micromachines (Basel)
                micromachines
                Micromachines
                MDPI
                2072-666X
                17 January 2018
                January 2018
                : 9
                : 1
                : 32
                Affiliations
                [1 ]Food, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada; martihua@ 123456mail.ubc.ca (M.Z.H.); shenmiao.ivy.li@ 123456gmail.com (S.L.)
                [2 ]Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin 300071, China; wangshuo@ 123456nankai.edu.cn
                Author notes
                [* ]Correspondence: xiaonan.lu@ 123456ubc.ca ; Tel.: +1-604-822-2551
                Author information
                https://orcid.org/0000-0003-3678-1956
                Article
                micromachines-09-00032
                10.3390/mi9010032
                6187612
                30393308
                306ca3f3-4d77-4a49-b554-ce17fe08b343
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 02 January 2018
                : 16 January 2018
                Categories
                Review

                μpads,chemical hazard,food safety,food contamination,sample preparation

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