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      How Frequent Are Hepatitis B Virus Markers in Adult Patients with Glomerular Diseases in a Low Endemic Country?

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          Abstract

          In order to appreciate the frequency of hepatitis B virus (HBV) infection in patients with glomerular diseases in France, a low endemic country, we reviewed the series of patients biopsied in the years 1983-1989 in 2 departments of nephrology differing by the characteristics of the population. In Saint-Brieuc, where the population is almost exclusively Caucasian, with nearly no immigrant, HBsAg was not detected in any of the 86 patients. In Paris, a large number of patients come from highly or intermediately endemic regions. HBsAg was detected in 3 of 209 patients, 2 of the 75 patients with membranous nephropathy and 1 of the 32 patients with minimal-change nephrotic syndrome. These patients came from Africa and Asia. Therefore, in low endemic countries, the role of HBV infection in the etiology of glomerulonephritis is minimal. But, because of the late severity of the disease, screening remains essential in patients belonging to the high-risk groups.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1993
          1993
          12 December 2008
          : 63
          : 4
          : 400-403
          Affiliations
          aDepartment of Nephrology und U.90 INSERM, and bBlood Transfusion, Department, Necker Hospital, Paris; cDepartment of Nephrology, La Beauchée Hospital, Saint-Brieuc; dDepartment of Pathology, Pontchaillou Hospital, Rennes; Blood eTransfusion Department, Saint-Brieuc; fU.155 INSERM, Paris, France
          Article
          187242 Nephron 1993;63:400–403
          10.1159/000187242
          8459874
          © 1993 S. Karger AG, Basel

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          Page count
          Pages: 4
          Categories
          Original Paper

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