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      Lead Toxicity: Health Hazards, Influence on Food Chain, and Sustainable Remediation Approaches

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          Abstract

          Lead (Pb) toxicity has been a subject of interest for environmental scientists due to its toxic effect on plants, animals, and humans. An increase in several Pb related industrial activities and use of Pb containing products such as agrochemicals, oil and paint, mining, etc. can lead to Pb contamination in the environment and thereby, can enter the food chain. Being one of the most toxic heavy metals, Pb ingestion via the food chain has proven to be a potential health hazard for plants and humans. The current review aims to summarize the research updates on Pb toxicity and its effects on plants, soil, and human health. Relevant literature from the past 20 years encompassing comprehensive details on Pb toxicity has been considered with key issues such as i) Pb bioavailability in soil, ii) Pb biomagnification, and iii) Pb- remediation, which has been addressed in detail through physical, chemical, and biological lenses. In the review, among different Pb-remediation approaches, we have highlighted certain advanced approaches such as microbial assisted phytoremediation which could possibly minimize the Pb load from the resources in a sustainable manner and would be a viable option to ensure a safe food production system.

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          Soil contamination in China: current status and mitigation strategies.

          China faces great challenges in protecting its soil from contamination caused by rapid industrialization and urbanization over the last three decades. Recent nationwide surveys show that 16% of the soil samples, 19% for the agricultural soils, are contaminated based on China’s soil environmental quality limits, mainly with heavy metals and metalloids. Comparisons with other regions of the world show that the current status of soil contamination, based on the total contaminant concentrations, is not worse in China. However, the concentrations of some heavy metals in Chinese soils appear to be increasing at much greater rates. Exceedance of the contaminant limits in food crops is widespread in some areas, especially southern China, due to elevated inputs of contaminants, acidic nature of the soil and crop species or cultivars prone to heavy metal accumulation. Minimizing the transfer of contaminants from soil to the food chain is a top priority. A number of options are proposed, including identification of the sources of contaminants to agricultural systems, minimization of contaminant inputs, reduction of heavy metal phytoavailability in soil with liming or other immobilizing materials, selection and breeding of low accumulating crop cultivars, adoption of appropriate water and fertilizer management, bioremediation, and change of land use to grow nonfood crops. Implementation of these strategies requires not only technological advances, but also social-economic evaluation and effective enforcement of environmental protection law.
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            Heavy metals in food crops: Health risks, fate, mechanisms, and management

            Food security is a high-priority issue for sustainable global development both quantitatively and qualitatively. In recent decades, adverse effects of unexpected contaminants on crop quality have threatened both food security and human health. Heavy metals and metalloids (e.g., Hg, As, Pb, Cd, and Cr) can disturb human metabolomics, contributing to morbidity and even mortality. Therefore, this review focuses on and describes heavy metal contamination in soil-food crop subsystems with respect to human health risks. It also explores the possible geographical pathways of heavy metals in such subsystems. In-depth discussion is further offered on physiological/molecular translocation mechanisms involved in the uptake of metallic contaminants inside food crops. Finally, management strategies are proposed to regain sustainability in soil-food subsystems.
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              Plants transfer lipids to sustain colonization by mutualistic mycorrhizal and parasitic fungi.

              Arbuscular mycorrhizal (AM) fungi facilitate plant uptake of mineral nutrients and draw organic nutrients from the plant. Organic nutrients are thought to be supplied primarily in the form of sugars. Here we show that the AM fungus Rhizophagus irregularis is a fatty acid auxotroph and that fatty acids synthesized in the host plants are transferred to the fungus to sustain mycorrhizal colonization. The transfer is dependent on RAM2 (REQUIRED FOR ARBUSCULAR MYCORRHIZATION 2) and the ATP binding cassette transporter-mediated plant lipid export pathway. We further show that plant fatty acids can be transferred to the pathogenic fungus Golovinomyces cichoracerum and are required for colonization by pathogens. We suggest that the mutualistic mycorrhizal and pathogenic fungi similarly recruit the fatty acid biosynthesis program to facilitate host invasion.
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                Author and article information

                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                25 March 2020
                April 2020
                : 17
                : 7
                : 2179
                Affiliations
                [1 ]School of Hydrology and Water Resources, Nanjing University of Information Science and Technology, Nanjing 210044, China; amitkdah@ 123456nuist.edu.cn
                [2 ]Central Muga Eri Research and Training Institute, Central Silk Board, Jorhat, Assam 785000, India; aftab.csb@ 123456gov.in (A.A.S.); subrahmanyamg.csb@ 123456gov.in (G.S.)
                [3 ]Geobiotec Research Centre, Department of Geosciences, University of Aveiro, 3810-193 Aveiro, Portugal; marinacp@ 123456ua.pt
                [4 ]Water Management (Agriculture) Division, Centre for Water Resources Development and Management, Kozhikode, Kerala 673571, India; ashispc@ 123456cwrdm.org
                [5 ]Central Sericultural Germplasm Resources Centre (CSGRC), Central Silk Board, Ministry of Textiles, Thally Road, Hosur, Tamil Nadu 635109, India; rmtarapur@ 123456gmail.com
                [6 ]ICAR-Central Arid Zone Research Institute Regional Research Station Pali Marwar, Rajasthan 342003, India; deepak.gupta@ 123456icar.gov.in
                [7 ]Institute of Soil, Water and Environmental Sciences, Agricultural Research Organization (ARO), The Volcani Center, Rishon LeZion 7505101, Israel; sanm@ 123456volcani.agri.gov.il
                [8 ]Department of Environment science, J.C. Bose University of Science & Technology, YMCA, NH-2, Sector-6, Mathura Road, Faridabad, Haryana 121006, India; smita@ 123456jcboseust.ac.in
                [9 ]Centre for Environment Science and Climate Resilient Agriculture, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India; shakeel.khan@ 123456icar.gov.in
                [10 ]Institute of Environment and Development Studies, Bundelkhand University, Kanpur Road, Jhansi 284128, India; envirokrishna@ 123456gmail.com
                Author notes
                [* ]Correspondence: amitkumar.csb@ 123456gov.in
                Author information
                https://orcid.org/0000-0002-6073-0860
                https://orcid.org/0000-0002-6908-1596
                https://orcid.org/0000-0001-9541-0931
                https://orcid.org/0000-0002-9294-7634
                https://orcid.org/0000-0002-4228-2726
                Article
                ijerph-17-02179
                10.3390/ijerph17072179
                7177270
                32218253
                35e8e056-cf16-4e0b-b84b-f775a94b0ba3
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 28 January 2020
                : 22 March 2020
                Categories
                Review

                Public health
                lead toxicity,lead contamination,health hazards,remediation
                Public health
                lead toxicity, lead contamination, health hazards, remediation

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