- Record: found
- Abstract: found
- Article: not found
Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial.
Eleonora Scorletti
1 ,
Annette L West
2 ,
Lokpal Bhatia
3 ,
Samuel P Hoile
2 ,
Keith G McCormick
3 ,
Graham C Burdge
2 ,
Karen A Lillycrop
2 ,
Geraldine F Clough
2 ,
Philip C Calder
3 ,
Christopher D Byrne
3
Dec 2015
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Genetic variation in both patatin-like phospholipase domain-containing protein-3 (PNPLA3) (I148M) and the transmembrane 6 superfamily member 2 protein (TM6SF2) (E167K) influences severity of liver disease, and serum triglyceride concentrations in non-alcoholic fatty liver disease (NAFLD), but whether either genotype influences the responses to treatments is uncertain.