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      Prospective insights into spinal surgery outcomes and adverse events: A comparative study between patients 65–79 years vs. ≥80 years from a German tertiary center

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          Abstract

          Introduction

          In light of an aging global population, understanding adverse events (AEs) in surgeries for older adults is crucial for optimal outcomes and patient safety.

          Research question

          Our study compares surgical outcomes and AEs in patients aged 65–79 with those aged ≥80, focusing on clinical outcomes, morbidity and mortality rates, and age-related risk factors for AEs.

          Material and methods

          Our study, from January 2019 to December 2022, involved patients aged 65–79 and ≥ 80 undergoing spinal surgery. Each patient was evaluated for AEs post-discharge, defined as negative clinical outcomes within 30 days post-surgery. Patients were categorized based on primary spinal diagnoses: degenerative, oncological, traumatic, and infectious.

          Results

          We enrolled 546 patients aged 65–79 and 184 octogenarians. Degenerative diseases were most common in both groups, with higher infection and tumor rates in the younger cohort. Octogenarians had a higher Charlson Comorbidity Index and longer ICU/hospital stays. Surgery-related AE rates were 8.1% for 65-79-year-olds and 15.8% for octogenarians, with mortality around 2% in both groups.

          Discussion and conclusion

          Our prospective analysis shows octogenarians are more susceptible to surgical AEs, linked to greater health complexities. Despite higher AEs in older patients, low mortality rates across both age groups highlight the safety of spinal surgery. Tracking AEs is crucial for patient communication and impacts healthcare accreditation and funding.

          Highlights

          • A comparative study of spinal surgery outcomes between patients aged 65–79 and those ≥80 years reveals that octogenarians experience a higher rate of surgery-related adverse events.

          • The research underscores the importance of considering age and comorbidities in predicting surgical adverse events.

          • Longer hospital stays were seen in octogenarians.

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          Most cited references26

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          Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.

          Although quality assessment is gaining increasing attention, there is still no consensus on how to define and grade postoperative complications. This shortcoming hampers comparison of outcome data among different centers and therapies and over time. A classification of complications published by one of the authors in 1992 was critically re-evaluated and modified to increase its accuracy and its acceptability in the surgical community. Modifications mainly focused on the manner of reporting life-threatening and permanently disabling complications. The new grading system still mostly relies on the therapy used to treat the complication. The classification was tested in a cohort of 6336 patients who underwent elective general surgery at our institution. The reproducibility and personal judgment of the classification were evaluated through an international survey with 2 questionnaires sent to 10 surgical centers worldwide. The new ranking system significantly correlated with complexity of surgery (P < 0.0001) as well as with the length of the hospital stay (P < 0.0001). A total of 144 surgeons from 10 different centers around the world and at different levels of training returned the survey. Ninety percent of the case presentations were correctly graded. The classification was considered to be simple (92% of the respondents), reproducible (91%), logical (92%), useful (90%), and comprehensive (89%). The answers of both questionnaires were not dependent on the origin of the reply and the level of training of the surgeons. The new complication classification appears reliable and may represent a compelling tool for quality assessment in surgery in all parts of the world.
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            Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases

            R Deyo (1992)
            Administrative databases are increasingly used for studying outcomes of medical care. Valid inferences from such data require the ability to account for disease severity and comorbid conditions. We adapted a clinical comorbidity index, designed for use with medical records, for research relying on International Classification of Diseases (ICD-9-CM) diagnosis and procedure codes. The association of this adapted index with health outcomes and resource use was then examined with a sample of Medicare beneficiaries who underwent lumbar spine surgery in 1985 (n = 27,111). The index was associated in the expected direction with postoperative complications, mortality, blood transfusion, discharge to nursing home, length of hospital stay, and hospital charges. These associations were observed whether the index incorporated data from multiple hospitalizations over a year's time, or just from the index surgical admission. They also persisted after controlling for patient age. We conclude that the adapted comorbidity index will be useful in studies of disease outcome and resource use employing administrative databases.
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              Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.

              It is uncertain whether bridging anticoagulation is necessary for patients with atrial fibrillation who need an interruption in warfarin treatment for an elective operation or other elective invasive procedure. We hypothesized that forgoing bridging anticoagulation would be noninferior to bridging with low-molecular-weight heparin for the prevention of perioperative arterial thromboembolism and would be superior to bridging with respect to major bleeding.
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                Author and article information

                Contributors
                Journal
                Brain Spine
                Brain Spine
                Brain & Spine
                Elsevier
                2772-5294
                17 February 2024
                2024
                17 February 2024
                : 4
                : 102768
                Affiliations
                [1]Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany
                Author notes
                Article
                S2772-5294(24)00024-9 102768
                10.1016/j.bas.2024.102768
                10951790
                38510610
                3734b262-a35a-4da0-a18f-37f83b6c2e7a
                © 2024 Published by Elsevier B.V. on behalf of EUROSPINE, the Spine Society of Europe, EANS, the European Association of Neurosurgical Societies.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 16 December 2023
                : 18 January 2024
                : 14 February 2024
                Categories
                Article

                aging population,spine surgery,adverse events
                aging population, spine surgery, adverse events

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