For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
6
views
40
references
 Top references
cited by
3
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      238
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Changes in the Epidemiology of Zoonotic Infections in Children : A Nationwide Register Study in Finland

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Supplemental Digital Content is available in the text.

          Objectives:

          Zoonotic infections are difficult to recognize in children. The age distributions and seasonal occurrences of these infections vary substantially, even among those transmitted by the same vectors, and their epidemiology may change over time. The aim was to report the incidences and trends of Borrelia burgdorferi, Puumala virus, Francisella tularensis and tick-borne encephalitis (TBE) virus infections in the pediatric population (age 0–19) of Finland.

          Methods:

          A nationwide survey based on the National Infectious Disease Register was conducted from 1996 to 2019 and all laboratory-confirmed cases were included. Age-stratified incidences per 100,000 person-years were calculated.

          Results:

          Cumulative incidences were B. burgdorferi 11.2, TBE 0.4, Puumala virus 6.4 and F. tularensis 2.5 per 100,000 person-years. An increasing trend in the incidences of B. burgdorferi and TBE was observed. Borrelia expanded geographically northward and inland. Tularemia follows a 2–4-year epidemic cycle and rates are similar across age groups. Puumala incidences are highest in the older children.

          Discussion:

          Borrelia infections increased most rapidly in children 5–9 years of age and overall expanded geographically in Finland. Tularemia epidemic cycles were shorter than those previously reported. These results will help clinicians to identify these infections in different geographic areas and age groups in Finland.

          Related collections

          Most cited references40

          • Record: found
          • Abstract: found
          • Article: not found

          Global trends in emerging infectious diseases

          Kate E. Jones, Nikkita G Patel, Marc A. Levy … (2008)
          The next new disease Emerging infectious diseases are a major threat to health: AIDS, SARS, drug-resistant bacteria and Ebola virus are among the more recent examples. By identifying emerging disease 'hotspots', the thinking goes, it should be possible to spot health risks at an early stage and prepare containment strategies. An analysis of over 300 examples of disease emerging between 1940 and 2004 suggests that these hotspots can be accurately mapped based on socio-economic, environmental and ecological factors. The data show that the surveillance effort, and much current research spending, is concentrated in developed economies, yet the risk maps point to developing countries as the more likely source of new diseases. Supplementary information The online version of this article (doi:10.1038/nature06536) contains supplementary material, which is available to authorized users.
          Article 0 comments Cited 1351 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Lyme borreliosis.

            Gerold Stanek, Gary Wormser, Jeremy Gray … (2012)
            Lyme borreliosis (Lyme disease) is caused by spirochaetes of the Borrelia burgdorferi sensu lato species complex, which are transmitted by ticks. The most common clinical manifestation is erythema migrans, which eventually resolves, even without antibiotic treatment. However, the infecting pathogen can spread to other tissues and organs, causing more severe manifestations that can involve a patient's skin, nervous system, joints, or heart. The incidence of this disease is increasing in many countries. Laboratory evidence of infection, mainly serology, is essential for diagnosis, except in the case of typical erythema migrans. Diagnosed cases are usually treated with antibiotics for 2-4 weeks and most patients make an uneventful recovery. No convincing evidence exists to support the use of antibiotics for longer than 4 weeks, or for the persistence of spirochaetes in adequately treated patients. Prevention is mainly accomplished by protecting against tick bites. There is no vaccine available for human beings. Copyright © 2012 Elsevier Ltd. All rights reserved.
            Article 0 comments Cited 399 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations.

              Anders Sjöstedt (2007)
              Francisella tularensis has been recognized as a human pathogen for almost 100 years and is the etiological agent of the zoonotic disease tularemia. Soon after its discovery, it became recognized as an important pathogen in several parts of the world, for example, in the United States and Soviet Union. The number of tularemia cases in the two countries peaked in the 1940s and has thereafter steadily declined. Despite this decline, there was still much interest in the pathogen in the 1950s and 1960s since it is highly infectious and transmissible by aerosol, rendering it a potent biothreat agent. In fact, it was one of the agents that was given the highest priority in the offensive programs of the United States and Soviet Union. After termination of the offensive programs in the 1960s, the interest in F. tularensis diminished significantly and little research was carried out for several decades. Outbreaks of tularemia during the last decade in Europe, for example, in Kosovo, Spain, and Scandinavia, led to a renewed public interest in the disease. This, together with a massive increase in the research funding, in particular in the United States since 2001, has resulted in a significant increase in the number of active Francisella researchers. This article summarizes, predominantly with a historical perspective, the epidemiology and clinical manifestations of tularemia and the physiology of F. tularensis.
              Article 0 comments Cited 182 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Pediatr Infect Dis J
                Journal ID (iso-abbrev): Pediatr Infect Dis J
                Journal ID (publisher-id): INF
                Title: The Pediatric Infectious Disease Journal
                Publisher: Lippincott Williams & Wilkins (Hagerstown, MD )
                ISSN (Print): 0891-3668
                ISSN (Electronic): 1532-0987
                Publication date (Electronic): 28 December 2021
                Publication date (Print): April 2022
                Volume: 41
                Issue: 4
                Pages: e113-e119
                Affiliations
                From the [* ]Institute of Clinical Medicine, Department of Pediatrics, University of Eastern Finland, Kuopio
                [† ]Department of Pediatrics, Mikkeli Central Hospital, Mikkeli
                [‡ ]Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland.
                Author notes
                Address for correspondence: Ilari Kuitunen, MD, PhD, Department of Pediatrics, Mikkeli Central Hospital, Porrassalmenkatu 35-37, 50130, Mikkeli, Finland. E-mail: ilari.kuitunen@ 123456uef.fi .
                Article
                Accession ID: 00006
                DOI: 10.1097/INF.0000000000003440
                PMC ID: 8920006
                PubMed ID: 34966137
                SO-VID: 39718901-5418-4fd7-9d5e-ae4c979db9db
                Copyright © Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.
                License:

                This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date accepted : 6 December 2021
                Categories
                Subject: Original Studies
                Custom metadata
                OPEN-ACCESS TRUE
                STATUS ONLINE-ONLY
                SDC T

                Keywords: zoonosis,borrelia burgdorferi,puumala virus,francisella tularensis,tick-borne encephalitis virus
                Data availability:
                Keywords: zoonosis, borrelia burgdorferi, puumala virus, francisella tularensis, tick-borne encephalitis virus

                Comments

                Comment on this article

                scite_

                Similar content238

                See all similar

                Cited by3

                See all cited by

                Most referenced authors431

                See all reference authors