Journal ID (nlm-ta): Proc Natl Acad Sci U S A
Journal ID (iso-abbrev): Proc Natl Acad Sci U S A
Journal ID (hwp): pnas
Journal ID (publisher-id): PNAS
Title:
Proceedings of the National Academy of Sciences of the United States of America
Publisher:
National Academy of Sciences
ISSN
(Print):
0027-8424
ISSN
(Electronic):
1091-6490
Publication date
(Electronic):
20
December
2021
Publication date
(Print):
28
December
2021
Publication date PMC-release: 20
December
2021
Volume: 118
Issue: 52
Electronic Location Identifier: e2115140118
Affiliations
[1]
aDepartment of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599;
[2]
bInstitute for Genomic Medicine at Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , New York, NY 10032;
[3]
cComprehensive Epilepsy Center, New York University Grossman School of Medicine , New York, NY 10016;
[4]
dSudden Unexplained Death in Childhood Foundation , Roseland, NJ 07068;
[5]
eNeuroscience Institute, New York University Grossman School of Medicine, New York University , New York, NY 10016;
[6]
fDepartment of Neuroscience and Physiology, New York University , New York, NY 10016;
[7]
gInstitute for Systems Genetics, New York University Grossman School of Medicine , New York, NY 10016;
[8]
hDepartment of Pediatrics, New York University Grossman School of Medicine , New York, NY 10016;
[9]
iDivision of Heart Rhythm Services, Department of Cardiovascular Medicine, Windland
Smith Rice Genetic Heart Rhythm Clinic and Windland Smith Rice Sudden Death Genomics
Laboratory, Mayo Clinic , Rochester, MN 55902;
[10]
jDivision of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine,
Windland Smith Rice Genetic Heart Rhythm Clinic and Windland Smith Rice Sudden Death
Genomics Laboratory, Mayo Clinic , Rochester, MN 55902;
[11]
kDepartment of Molecular Pharmacology & Experimental Therapeutics, Windland Smith Rice
Genetic Heart Rhythm Clinic and Windland Smith Rice Sudden Death Genomics Laboratory,
Mayo Clinic , Rochester, MN 55902;
[12]
lDepartment of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, MN 55902
Author notes
Contributed by Richard W. Tsien, October 17, 2021 (sent for review August 17, 2021;
reviewed by Alfred L. George and Geoffrey S. Pitt)
Author contributions: M.H., L.G., X.W., G.G., R.M., M.T.M., D.B.G., R.W.T., and O.D.
designed research; M.H., L.G., X.W., G.G., R.M., and R.R. performed research; M.H.,
L.G., X.W., G.G., R.M., M.T.M., D.B.G., R.W.T., and O.D. analyzed data; R.R., M.J.A.,
D.J.T., P.T.L., J.G.P., M.T.M., D.B.G., and O.D. contributed new reagents/analytic
tools; and M.H., L.G., X.W., G.G., R.W.T., and O.D. wrote the paper.
1M.H., L.G., and X.W. contributed equally to this work.
Author information
Article
Publisher ID:
202115140
DOI: 10.1073/pnas.2115140118
PMC ID: 8719874
PubMed ID: 34930847
SO-VID: 3cb9dc7a-d079-41e9-b9d7-c4f0cae891fb
Copyright © Copyright © 2021 the Author(s). Published by PNAS.
License:
This open access article is distributed under
Creative Commons Attribution License 4.0 (CC BY).
Funded by: SUDC Foundation
Award ID: NA
Award Recipient
: Matthew Halvorsen
Award Recipient
: Laura Gould
Award Recipient
: Xiaohan Wang
Award Recipient
: Gariel Grant
Award Recipient
: Raquel Moya
Award Recipient
: Rachel Rabin
Award Recipient
: Michael J. Ackerman
Award Recipient
: David J. Tester
Award Recipient
: Peter T Lin
Award Recipient
: John G Pappas
Award Recipient
: Matthew Maurano
Award Recipient
: David B Goldstein
Award Recipient
: Richard W. Tsien
Award Recipient
: Orrin Devinsky
Funded by: Finding A Cure for Epilepsy and Seizures (FACES)
100007321
Award ID: NA
Award Recipient
: Matthew Halvorsen
Award Recipient
: Laura Gould
Award Recipient
: Xiaohan Wang
Award Recipient
: Gariel Grant
Award Recipient
: Raquel Moya
Award Recipient
: Rachel Rabin
Award Recipient
: Michael J. Ackerman
Award Recipient
: David J. Tester
Award Recipient
: Peter T Lin
Award Recipient
: John G Pappas
Award Recipient
: Matthew Maurano
Award Recipient
: David B Goldstein
Award Recipient
: Richard W. Tsien
Award Recipient
: Orrin Devinsky
Funded by: HHS | NIH | National Institute on Drug Abuse (NIDA)
100000026
Award ID: DA040484
Award Recipient
: Xiaohan Wang
Award Recipient
: Gariel Grant
Award Recipient
: Raquel Moya
Award Recipient
: Richard W. Tsien
Funded by: HHS | NIH | National Institute of Mental Health (NIMH)
100000025
Award ID: MH71739
Award Recipient
: Xiaohan Wang
Award Recipient
: Gariel Grant
Award Recipient
: Raquel Moya
Award Recipient
: Richard W. Tsien
Funded by: Mayo Clinic Windland Smith Rice Comprehensive Sudden Cardiac Death Program
Award ID: NA
Award Recipient
: Matthew Halvorsen
Award Recipient
: Laura Gould
Award Recipient
: Xiaohan Wang
Award Recipient
: Gariel Grant
Award Recipient
: Raquel Moya
Award Recipient
: Rachel Rabin
Award Recipient
: Michael J. Ackerman
Award Recipient
: David J. Tester
Award Recipient
: Peter T Lin
Award Recipient
: John G Pappas
Award Recipient
: Matthew Maurano
Award Recipient
: David B Goldstein
Award Recipient
: Richard W. Tsien
Award Recipient
: Orrin Devinsky