4
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      The discovery of an in situ Neanderthal remain in the Bawa Yawan Rockshelter, West-Central Zagros Mountains, Kermanshah

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Neanderthal extinction has been a matter of debate for many years. New discoveries, better chronologies and genomic evidence have done much to clarify some of the issues. This evidence suggests that Neanderthals became extinct around 40,000–37,000 years before present (BP), after a period of coexistence with Homo sapiens of several millennia, involving biological and cultural interactions between the two groups. However, the bulk of this evidence relates to Western Eurasia, and recent work in Central Asia and Siberia has shown that there is considerable local variation. Southwestern Asia, despite having a number of significant Neanderthal remains, has not played a major part in the debate over extinction. Here we report a Neanderthal deciduous canine from the site of Bawa Yawan in the West-Central Zagros Mountains of Iran. The tooth is associated with Zagros Mousterian lithics, and its context is preliminary dated to between ~43,600 and ~41,500 years ago.

          Related collections

          Most cited references62

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Re-epithelialization and immune cell behaviour in an ex vivo human skin model

          A large body of literature is available on wound healing in humans. Nonetheless, a standardized ex vivo wound model without disruption of the dermal compartment has not been put forward with compelling justification. Here, we present a novel wound model based on application of negative pressure and its effects for epidermal regeneration and immune cell behaviour. Importantly, the basement membrane remained intact after blister roof removal and keratinocytes were absent in the wounded area. Upon six days of culture, the wound was covered with one to three-cell thick K14+Ki67+ keratinocyte layers, indicating that proliferation and migration were involved in wound closure. After eight to twelve days, a multi-layered epidermis was formed expressing epidermal differentiation markers (K10, filaggrin, DSG-1, CDSN). Investigations about immune cell-specific manners revealed more T cells in the blister roof epidermis compared to normal epidermis. We identified several cell populations in blister roof epidermis and suction blister fluid that are absent in normal epidermis which correlated with their decrease in the dermis, indicating a dermal efflux upon negative pressure. Together, our model recapitulates the main features of epithelial wound regeneration, and can be applied for testing wound healing therapies and investigating underlying mechanisms.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found
            Is Open Access

            THE INTCAL20 NORTHERN HEMISPHERE RADIOCARBON AGE CALIBRATION CURVE (0–55 CAL kBP)

            Radiocarbon ( 14 C) ages cannot provide absolutely dated chronologies for archaeological or paleoenvironmental studies directly but must be converted to calendar age equivalents using a calibration curve compensating for fluctuations in atmospheric 14 C concentration. Although calibration curves are constructed from independently dated archives, they invariably require revision as new data become available and our understanding of the Earth system improves. In this volume the international 14 C calibration curves for both the Northern and Southern Hemispheres, as well as for the ocean surface layer, have been updated to include a wealth of new data and extended to 55,000 cal BP. Based on tree rings, IntCal20 now extends as a fully atmospheric record to ca. 13,900 cal BP. For the older part of the timescale, IntCal20 comprises statistically integrated evidence from floating tree-ring chronologies, lacustrine and marine sediments, speleothems, and corals. We utilized improved evaluation of the timescales and location variable 14 C offsets from the atmosphere (reservoir age, dead carbon fraction) for each dataset. New statistical methods have refined the structure of the calibration curves while maintaining a robust treatment of uncertainties in the 14 C ages, the calendar ages and other corrections. The inclusion of modeled marine reservoir ages derived from a three-dimensional ocean circulation model has allowed us to apply more appropriate reservoir corrections to the marine 14 C data rather than the previous use of constant regional offsets from the atmosphere. Here we provide an overview of the new and revised datasets and the associated methods used for the construction of the IntCal20 curve and explore potential regional offsets for tree-ring data. We discuss the main differences with respect to the previous calibration curve, IntCal13, and some of the implications for archaeology and geosciences ranging from the recent past to the time of the extinction of the Neanderthals.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              The complete genome sequence of a Neandertal from the Altai Mountains

              We present a high-quality genome sequence of a Neandertal woman from Siberia. We show that her parents were related at the level of half siblings and that mating among close relatives was common among her recent ancestors. We also sequenced the genome of a Neandertal from the Caucasus to low coverage. An analysis of the relationships and population history of available archaic genomes and 25 present-day human genomes shows that several gene flow events occurred among Neandertals, Denisovans and early modern humans, possibly including gene flow into Denisovans from an unknown archaic group. Thus, interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene. In addition, the high quality Neandertal genome allows us to establish a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neandertals and Denisovans.
                Bookmark

                Author and article information

                Contributors
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SoftwareRole: SupervisionRole: ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review & editing
                Role: Data curationRole: InvestigationRole: MethodologyRole: SoftwareRole: Writing – original draftRole: Writing – review & editing
                Role: Data curationRole: InvestigationRole: MethodologyRole: SoftwareRole: VisualizationRole: Writing – original draft
                Role: InvestigationRole: MethodologyRole: Writing – original draft
                Role: Data curationRole: Investigation
                Role: MethodologyRole: SoftwareRole: Visualization
                Role: Visualization
                Role: InvestigationRole: Visualization
                Role: Investigation
                Role: InvestigationRole: Writing – original draft
                Role: Methodology
                Role: Data curationRole: InvestigationRole: Writing – original draft
                Role: Writing – original draft
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                26 August 2021
                2021
                : 16
                : 8
                : e0253708
                Affiliations
                [1 ] Stiftung Neanderthal Museum, Mettmann, Germany
                [2 ] Department of Prehistoric Archaeology University of Cologne, Cologne, Germany
                [3 ] DiyarMehr Centre for Palaeolithic Research, Kermanshah, Iran
                [4 ] Department of Cultural Heritage, University of Bologna, Bologna, Italy
                [5 ] Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
                [6 ] Department of Chemistry G. Ciamician, Alma Mater Studiorum, University of Bologna, Bologna, Italy
                [7 ] Department of Archaeology, University of Mohaghegh Ardabili University, Ardabil, Iran
                [8 ] Department of Architecture, Faculty of Art and Architecture, Bu-Ali Sina University, Hamedan, Iran
                [9 ] Department of Physical Geography, University of Tehran, Tehran, Iran
                [10 ] Collège de France, 11 Place Marcelin Berthelot, Paris, France
                [11 ] Leverhulme Centre for Human Evolutionary Studies, Department of Archaeology, University of Cambridge, Cambridge, United Kingdom
                University of Florence, ITALY
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                https://orcid.org/0000-0002-7668-8804
                https://orcid.org/0000-0002-8295-2560
                Article
                PONE-D-21-00463
                10.1371/journal.pone.0253708
                8389444
                34437543
                3e59a006-aa25-43f4-9525-10c20d77057f
                © 2021 Heydari-Guran et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 6 January 2021
                : 11 June 2021
                Page count
                Figures: 9, Tables: 7, Pages: 24
                Funding
                Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
                Award ID: 423897519
                Award Recipient :
                Funding was provided from Deutsche Forschungsgemeinschaft (Grant 423897519) to SHG.
                Categories
                Research Article
                Biology and Life Sciences
                Paleontology
                Paleoanthropology
                Archaic Humans
                Hominids
                Hominins
                Neanderthals
                Earth Sciences
                Paleontology
                Paleoanthropology
                Archaic Humans
                Hominids
                Hominins
                Neanderthals
                Social Sciences
                Anthropology
                Physical Anthropology
                Paleoanthropology
                Archaic Humans
                Hominids
                Hominins
                Neanderthals
                Biology and Life Sciences
                Physical Anthropology
                Paleoanthropology
                Archaic Humans
                Hominids
                Hominins
                Neanderthals
                Biology and Life Sciences
                Paleontology
                Paleoanthropology
                Earth Sciences
                Paleontology
                Paleoanthropology
                Social Sciences
                Anthropology
                Physical Anthropology
                Paleoanthropology
                Biology and Life Sciences
                Physical Anthropology
                Paleoanthropology
                Social Sciences
                Archaeology
                Archaeological Dating
                Radioactive Carbon Dating
                Research and Analysis Methods
                Chemical Characterization
                Isotope Analysis
                Radioactive Carbon Dating
                Social Sciences
                Archaeology
                Biology and Life Sciences
                Anatomy
                Digestive System
                Teeth
                Medicine and Health Sciences
                Anatomy
                Digestive System
                Teeth
                Biology and Life Sciences
                Anatomy
                Head
                Jaw
                Teeth
                Medicine and Health Sciences
                Anatomy
                Head
                Jaw
                Teeth
                Earth Sciences
                Atmospheric Science
                Climatology
                Paleoclimatology
                Biology and Life Sciences
                Paleontology
                Paleoclimatology
                Earth Sciences
                Paleontology
                Paleoclimatology
                Biology and Life Sciences
                Paleontology
                Paleoanthropology
                Lithic Technology
                Earth Sciences
                Paleontology
                Paleoanthropology
                Lithic Technology
                Social Sciences
                Anthropology
                Physical Anthropology
                Paleoanthropology
                Lithic Technology
                Biology and Life Sciences
                Physical Anthropology
                Paleoanthropology
                Lithic Technology
                Earth Sciences
                Geology
                Petrology
                Sediment
                Earth Sciences
                Geology
                Sedimentary Geology
                Sediment
                Custom metadata
                All relevant data are within the paper.

                Uncategorized
                Uncategorized

                Comments

                Comment on this article