Resolution of Hepatitis B Viremia in a Renal Transplant Recipient Treated with Alpha-2b Interferon

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Abstract

A renal transplant patient developed symptomatic hepatitis after withdrawal from corticosteroids. Tests for hepatitis B e antigen and hepatitis B viral DNA were both positive prior to treatment with 1 million units alpha interferon three times weekly for 3 weeks followed by an increase to 3 million units alpha interferon three times weekly for a total of 16 weeks. At the end of treatment, hepatitis had clinically resolved with conversion to a hepatitis B e antibody positive and hepatitis B e antigen and viral DNA negative state. The renal allograft function remained excellent throughout the course of therapy with interferon.

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Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1998

Publication date (Print): August 1998

Publication date (Electronic): 29 July 1998

Volume: 79

Issue: 4

Pages: 469-471

Affiliations

Departments of ^a Medicine and ^b Surgery, and ^c Institute of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, and ^d Transplantation Service, University Hospitals of Cleveland, Ohio, USA

Article

Publisher ID: 45094 Other ID: Nephron 1998;79:469–471

DOI: 10.1159/000045094

PubMed ID: 9689164

SO-VID: 3e7ee9d0-6a97-4b41-b288-d0696a714510

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Resolution of Hepatitis B Viremia in a Renal Transplant Recipient Treated with Alpha-2b Interferon

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Karger: Nephrology

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