Indoleamine 2,3-dioxygenase and immune changes under antidepressive treatment in major depression in females.

Zoga, Margarita; Oulis, Panagiotis; Chatzipanagiotou, Stylianos; Masdrakis, Vasilios G.; Pliatsika, Paraskevi; Boufidou, Fotini; Foteli, Stefania; Soldatos, Constantin R; Nikolaou, Chryssoula; Papageorgiou, Charalampos

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Indoleamine 2,3-dioxygenase and immune changes under antidepressive treatment in major depression in females.

Author(s): Margarita Zoga ¹ , Panagiotis Oulis ² , Stylianos Chatzipanagiotou ³ , Vasilios G Masdrakis ² , Paraskevi Pliatsika ¹ , Fotini Boufidou ¹ , Stefania Foteli ¹ , Constantin R Soldatos ² , Chryssoula Nikolaou ¹ , Charalampos Papageorgiou ²

Publication date (Electronic): July 2 2014

Journal: In vivo (Athens, Greece)

Keywords: IDO, Major depressive disorder, antidepressive treatment, inflammatory mediators, serotonin

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Abstract

Indoleamine 2, 3-dioxygenase (IDO) induction has been suggested as a mechanism by which immune activation affects tryptophan metabolism and serotonin synthesis in major depressive disorder (MDD). We investigated IDO and changes in inflammatory mediators in patients with MDD undergoing effective treatment.

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Journal ID (iso-abbrev): In Vivo

Title: In vivo (Athens, Greece)

ISSN (Electronic): 1791-7549

ISSN (Print): 0258-851X

Publication date (Electronic): July 2 2014

Volume: 28

Issue: 4

Affiliations

[1 ] Laboratory of Biopathology and Immunology, Athens University Medical School, Eginition Hospital, Athens, Greece.

[2 ] First Department of Psychiatry, Eginition Hospital, Athens University Medical School, Athens, Greece.

[3 ] Laboratory of Biopathology and Immunology, Athens University Medical School, Eginition Hospital, Athens, Greece schatzi@med.uoa.gr schatzipa@gmail.com.

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Publisher Item ID: 28/4/633

PubMed ID: 24982234

SO-VID: 3efc8f88-2871-4dc9-b169-6d02865b3d28

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Keywords: IDO,Major depressive disorder,antidepressive treatment,inflammatory mediators,serotonin

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Keywords: IDO, Major depressive disorder, antidepressive treatment, inflammatory mediators, serotonin

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Indoleamine 2,3-dioxygenase and immune changes under antidepressive treatment in major depression in females.

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Serotonin and BEYOND

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