Hypercholesterolaemia and Hypertriglyceridaemia in Patients with Analgesic Nephropathy

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Abstract

Patients with analgesic nephropathy are reported to have a higher risk of atherosclerosis. One possible reason for this is a high incidence of hyperlipaemia in patients with analgesic nephropathy. In a retrospective study, serum cholesterol and serum triglyceride concentrations of patients with analgesic nephropathy and moderately restricted renal function were significantly higher compared to a control group with other renal diseases of similar age and degree of renal insufficiency. Hyperlipaemia in analgesic nephropathy is not explained by end-stage renal failure on one side or protein loss as in nephrotic syndrome on the other side. Some possible mechanisms for hyperlipaemia in analgesic nephropathy are discussed.

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Author and article information

Journal

Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1980

Publication date (Print): 1980

Publication date (Electronic): 02 December 2008

Volume: 26

Issue: 3

Pages: 111-115

Affiliations

Medizinische Klinik Köln-Merheim und Medizinische Poliklinik der Universität Köln (Direktor: Prof. W. Kaufmann); Medizinische Klinik I Köln-Merheim (Chefarzt: Prof. E. Renner), and Abteilung für klinische Chemie der Universität Köln (Leiter: Prof. K. Oette), Köln

Article

Publisher ID: 181964 Other ID: Nephron 1980;26:111–115

DOI: 10.1159/000181964

PubMed ID: 7412966

SO-VID: 4148d4dd-f79f-4bbc-9cb6-99f95379a6bc

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date accepted : 29 January 1980

Page count

Pages: 5

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