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Abstract
In diffusion-weighted MRI (DWI), image contrast is determined by the random microscopic
motion of water protons. During the last years, DWI has become an important modality
in the diagnostic work-up of acute ischemia in the CNS. There are also a few promising
reports about the application of DWI to other regions in the human body, such as the
vertebral column or the abdomen. This manuscript provides an introduction into the
basics of DWI and Diffusion Tensor imaging. The potential of various MR sequences
in concert with diffusion preparation are discussed with respect to acquisition speed,
spatial resolution, and sensitivity to bulk physiologic motion. More advanced diffusion
measurement techniques, such as high angular resolution diffusion imaging, are also
addressed.
Copyright 2002 Elsevier Science Ireland, Ltd.