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      Common and uncommon lesions of the vulva and vagina on magnetic resonance imaging: correlations with pathological findings

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          Abstract

          Vulvar and vaginal lesions representing a wide spectrum of diseases in female lower genital tract diseases make up a small part of all gynecological etiologies. Many of them are rare etiologies and are reported in case-reports studies. Translabial and transperineal ultrasound are modalities of choice for the first evaluation of perineal lesions. MRI is usually performed to determine the etiology of the lesions and stage. Benign lesions of the vulva and vagina usually manifest as simple cystic (vestibular cyst or endometrioma) or solid lesions (leiomyoma or angiofibroblastoma), while malignancies usually appear as large, solid masses and fill into both vaginal and perineal area. Post-contrast images play an important role in establishing a differential diagnosis, however, some benign lesions can also exhibit a vivid enhancement. Knowledge about radiologic-associated pathological manifestations may aid clinicians in better understanding these pathologies, especially for some rare lesions, and making a proper diagnosis before invasive procedures.

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          Most cited references48

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          Pathogenesis and pathophysiology of endometriosis.

          Originally described over three hundred years ago, endometriosis is classically defined by the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is an inflammatory, estrogen-dependent condition associated with pelvic pain and infertility. This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae. A thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential to the development of novel diagnostic and treatment approaches for this debilitating condition. Copyright © 2012 American Society for Reproductive Medicine. All rights reserved.
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            Melanoma: epidemiology, risk factors, pathogenesis, diagnosis and classification.

            This article reviews epidemiology, risk factors, pathogenesis and diagnosis of melanoma. Data on melanoma from the majority of countries show a rapid increase of the incidence of this cancer, with a slowing of the rate of incidence in the period 1990-2000. Males are approximately 1.5-times more likely to develop melanoma than females, while according to other studies, the different prevalence in both sexes must be analyzed in relation with age: the incidence rate of melanoma is grater in women than men until they reach the age of 40 years, however, by 75 years of age, the incidence is almost 3-times as high in men versus women. The most important and potentially modifiable environmental risk factor for developing malignant melanoma is the exposure to ultraviolet (UV) rays because of their genotoxic effect. Artificial UV exposure may play a role in the development of melanoma. The most important host risk factors are the number of melanocytic nevi, familiar history and genetic susceptibility. A patient with a personal history of melanoma must be considered at greater risk for subsequent melanoma. Indeed approximately 1-8% of patients with prior history of melanoma will develop multiple primary melanomas. We herein review the dermatological diagnosis and classification of melanoma.
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              Extra-Pelvic Endometriosis: A Systematic Review

              To conduct a systematic review of the literature on patients with extrapelvic deep endometriosis.
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                Author and article information

                Contributors
                Journal
                BJR Open
                BJR Open
                bjro
                BJR Open
                The British Institute of Radiology.
                2513-9878
                2023
                28 June 2023
                : 5
                : 1
                : 20230002
                Affiliations
                [1 ] org-divisionDepartment of Pathology, Obstetrics and Gynecology Hospital, Fudan University , Shanghai, China
                [2 ] org-divisionDepartment of Radiology, Shenzhen People's Hospital, 2nd Clinical Medical College of Jinan University, 1st Affiliated Hospital of Southern University of Science and Technology, P.R. China , ShenZhen, China
                [3 ] org-divisionDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University , Shanghai, China
                Author notes
                Address correspondence to: Dr He Zhang. E-mail: zhanghe1790@ 123456fckyy.org.cn
                Author information
                https://orcid.org/0000-0003-3782-1411
                Article
                BJRO-D-23-00002
                10.1259/bjro.20230002
                10302693
                37389007
                42402eb7-5755-409b-bb3e-87c0bfb14546
                © 2023 The Authors. Published by the British Institute of Radiology

                This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

                History
                : 25 March 2023
                : 12 May 2023
                : 12 May 2023
                Page count
                Figures: 11, Tables: 1, Equations: 0, References: 48, Pages: 10, Words: 7443
                Categories
                Diagnostic Radiology: Review article
                bjro, BJRO
                obs-gyn, Obstetrics and gynaecology
                mri, MRI

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