For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
5
views
4
references
 Top references
cited by
2
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      596
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Gastric syphilis: The great imitator in the stomach

      brief-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Syphilis is resurging worldwide. Here, we present the case of a 33-year-old heterosexual man who presented with a 3-week history of epigastric pain, nausea, emesis, and 8 kg weight loss. He was subsequently diagnosed with gastric syphilis, based on reactive syphilis serological testing and Treponema pallidum found in gastric biopsy specimens. Gastric syphilis is a rare presentation observed in 1% of cases and usually develops in secondary syphilis. Given the nonspecific manifestation and findings, a high index of suspicion is required for diagnosis of gastric syphilis.

          Related collections

          Most cited references4

          • Record: found
          • Abstract: found
          • Article: not found

          Diagnosis of gastric syphilis by direct immunofluorescence staining and real-time PCR testing.

          Tai-Yen Chen, Kevin W. George, Amitabh Srivastava … (2006)
          We report on a case of gastric syphilis in a patient with chronic dyspepsia. The diagnosis was established by serology and the demonstration of spirochetes in diffusely inflammed gastric mucosa by staining with a fluorescent monoclonal antibody specific for pathogenic treponemes and by the detection of specific treponemal DNA sequences by a real-time PCR.
          Article 0 comments Cited 21 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Gastric syphilis: a systematic review of published cases of the last 50 years.

            Vasilios Papastamopoulos, Michael Samarkos, Eleni E Mylona … (2010)
            The authors conducted a systematic review of the English literature for cases of Gastric Syphilis (GS) in the last 50 years. The 34 studies which met selection criteria included 52 patients with GS. Of the reviewed patients, only 13% had a history of syphilis diagnosis and 46% had prior or concurrent clinical manifestations of the disease. Epigastric pain/fullness was the most common presenting symptom (92%) and epigastric tenderness being the most common sign. Gastric bleeding of variable intensity was documented in 35% of the cases. In the radiologic examinations, fibrotic narrowing and rigidity of the gastric wall was the most common finding (43%), followed by hypertrophic and irregular folds, while in endoscopy the most common lesion types were multiple ulcerations (48%), nodular mucosa, and erosions. The antrum was the most commonly affected area (56%). The majority of the patients received penicillin (83%) with a rapid resolution of their symptoms. Seventeen percent of the patients were treated surgically either due to a complication or due to strong suspicion of infiltrating tumor or lymphoma. The nonspecific clinical, radiologic, and pathologic characteristics of GS can establish it as a great imitator of other gastric diseases. GS should be considered in the differential diagnosis in patients at risk for sexually transmitted diseases who present with abdominal complaints and unusual endoscopic lesions and no other diagnosis is made, irrespective of the presence of H. pylori. The absence of primary or secondary luetic lesions should not deter one from considering GS.
            Article 0 comments Cited 11 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Gastric syphilis: a disease with multiple manifestations.

              M J Atten, B Attar, E Teopengco … (1994)
              The resurgence of syphilis in the United States is effecting all areas of medical care. We describe a young female presenting with symptoms of peptic ulcer disease who failed to respond to H2-receptor antagonist therapy. After further evaluation, she was diagnosed with gastric syphilis and responded well to penicillin. Because gastric syphilis has no pathognomonic clinical findings, the clinician needs to be aware of this disease entity so as to make the correct diagnosis and institute the appropriate antibiotic therapy.
              Article 0 comments Cited 5 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Shuji Hatakeyama
                Journal
                Journal ID (nlm-ta): IDCases
                Journal ID (iso-abbrev): IDCases
                Title: IDCases
                Publisher: Elsevier
                ISSN (Electronic): 2214-2509
                Publication date PMC-release: 21 March 2018
                Publication date Collection: 2018
                Publication date (Electronic): 21 March 2018
                Volume: 12
                Pages: 97-98
                Affiliations
                [a ]Department of Internal Medicine, Tokyo Metropolitan Health and Medical Treatment Corporation Ohkubo Hospital, Tokyo, Japan
                [b ]Department of Infectious Diseases, University of Tokyo Hospital, Tokyo, Japan
                [c ]Division of General Internal Medicine/Infectious Diseases, Jichi Medical University Hospital, Tochigi, Japan
                Author notes
                [* ]Corresponding author at: Division of General Internal Medicine/Infectious Diseases, Jichi Medical University Hospital, Tochigi, Japan. shatake-tky@ 123456umin.ac.jp
                [1]

                Present address: Yakushiji 3311-1, Simono-shi, Tochigi 329-0498, Japan.

                Article
                Publisher ID: S2214-2509(18)30054-4
                DOI: 10.1016/j.idcr.2018.03.015
                PMC ID: 6010960
                SO-VID: 4387e290-4d15-407e-b65f-ed9812be665f
                Copyright © © 2018 The Authors
                License:

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                Categories
                Subject: Article

                Keywords: gastric syphilis,gastritis,secondary syphilis
                Data availability:
                Keywords: gastric syphilis, gastritis, secondary syphilis

                Comments

                Comment on this article

                scite_

                Similar content596

                See all similar

                Cited by2

                See all cited by

                Most referenced authors55

                See all reference authors