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      Evaluating the anxiety and depression status of prostate cancer patients whose operations were postponed because of the COVID‐19 pandemic

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          Abstract

          Aim

          In this study, we aimed to evaluate the anxiety and depression status of prostate cancer (PCa) patients whose planned operations in the urology clinic of our hospital, which is serving as a pandemic hospital in Turkey have been postponed because of the coronavirus disease 2019 pandemic.

          Methods

          This survey study was conducted at urology clinic of Ankara City Hospital between March 1 and June 1, 2020, and included 24 male patients who agreed to answer the questionnaires (State‐Trait Anxiety Inventory [STAI] I and II and Beck Depression Inventory [BDI]). Demographical and clinical data (age, time since diagnosis, total serum prostate‐specific antigen (PSA) levels, risk groups according to the D'Amico classification system, smoking, alcohol habitus, major surgical history and comorbidities) of the patients were collected from hospital software.

          Results

          The mean STAI‐I score of the patients (46.7 ± 1.4 [44‐49]) was significantly higher than their STAI‐II score (41.7 ± 2.4 [39‐47]) ( P < .001). The negative correlation between the decrease in age and STAI‐I score was found to be statistically significant ( r = 0.439, P < .05). The mean BDI score of the patients was 4.3 ± 3.2 (0‐13), which was compatible with mild depression. There was no statistically significant difference among the time elapsed from diagnosis, PSA levels, smoking and alcohol habitus, major surgical history and comorbidity status and STAI‐I, STAI‐II and BDI scores ( P > .05).

          Conclusion

          Prostate cancer patients with postponed operations should be guided properly in order to manage their anxiety status especially young patients.

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          Most cited references17

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          EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer—2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

          To present a summary of the 2020 version of the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Society of Urogenital Radiology (ESUR)-International Society of Geriatric Oncology (SIOG) guidelines on screening, diagnosis, and local treatment of clinically localised prostate cancer (PCa).
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            Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer.

            Interstitial radiation (implant) therapy is used to treat clinically localized adenocarcinoma of the prostate, but how it compares with other treatments is not known. To estimate control of prostate-specific antigen (PSA) after radical prostatectomy (RP), external beam radiation (RT), or implant with or without neoadjuvant androgen deprivation therapy in patients with clinically localized prostate cancer. Retrospective cohort study of outcome data compared using Cox regression multivariable analyses. A total of 1872 men treated between January 1989 and October 1997 with an RP (n = 888) or implant with or without neoadjuvant androgen deprivation therapy (n = 218) at the Hospital of the University of Pennsylvania, Philadelphia, or RT (n = 766) at the Joint Center for Radiation Therapy, Boston, Mass, were enrolled. Actuarial freedom from PSA failure (defined as PSA outcome). The relative risk (RR) of PSA failure in low-risk patients (stage T1c, T2a and PSA level 10 and 20 ng/mL or Gleason score > or =8) treated with implant compared with RP were 3.1 (95% CI, 1.5-6.1) and 3.0 (95% CI, 1.8-5.0), respectively. The addition of androgen deprivation to implant therapy did not improve PSA outcome in high-risk patients but resulted in a PSA outcome that was not statistically different compared with the results obtained using RP or RT in intermediate-risk patients. These results were unchanged when patients were stratified using the traditional rankings of biopsy Gleason scores of 2 through 4 vs 5 through 6 vs 7 vs 8 through 10. Low-risk patients had estimates of 5-year PSA outcome after treatment with RP, RT, or implant with or without neoadjuvant androgen deprivation that were not statistically different, whereas intermediate- and high-risk patients treated with RP or RT did better then those treated by implant. Prospective randomized trials are needed to verify these findings.
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              The development of a six-item short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI).

              Two studies are reported describing the development of a short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI) for use in circumstances where the full-form is inappropriate. Using item-remainder correlations, the most highly correlated anxiety-present and anxiety-absent items were combined, and correlated with scores obtained using the full-form of the STAI. Correlation coefficients greater than .90 were obtained using four and six items from the STAI. Acceptable reliability and validity were obtained using six items. The use of this six-item short-form produced scores similar to those obtained using the full-form. This was so for several groups of subjects manifesting a range of anxiety levels. This short-form of the STAI is therefore sensitive to fluctuations in state anxiety. When compared with the full-form of the STAI, the six-item version offers a briefer and just as acceptable scale for subjects while maintaining results that are comparable to those obtained using the full-form of the STAI.
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                Author and article information

                Contributors
                yalcinkizilkan@yahoo.com
                Journal
                Int J Clin Pract
                Int J Clin Pract
                10.1111/(ISSN)1742-1241
                IJCP
                International Journal of Clinical Practice
                John Wiley and Sons Inc. (Hoboken )
                1368-5031
                1742-1241
                26 May 2021
                : e14278
                Affiliations
                [ 1 ] Department of Urology Ankara City Hospital Ankara Turkey
                Author notes
                [*] [* ] Correspondence

                Yalcin Kizilkan, Ankara City Hospital, Department of Urology, Ankara, Üniversiteler, Bilkent Blv. No: 1, 06800 Çankaya, Ankara, Turkey.

                Email: yalcinkizilkan@ 123456yahoo.com

                Author information
                https://orcid.org/0000-0002-4729-0100
                Article
                IJCP14278
                10.1111/ijcp.14278
                8236926
                33914983
                4406e25b-6f5b-411f-b734-a38f25fb2add
                © 2021 John Wiley & Sons Ltd

                This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

                History
                : 17 December 2020
                : 26 April 2021
                Page count
                Figures: 0, Tables: 3, Pages: 5, Words: 6769
                Categories
                Original Article
                Original Articles
                Urology
                Custom metadata
                2.0
                corrected-proof
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.0.2 mode:remove_FC converted:28.06.2021

                Medicine
                Medicine

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