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      Surgical (Open and laparoscopic) management of large difficult CBD stones after different sessions of endoscopic failure: A retrospective cohort study

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          Abstract

          Objectives

          For complicated common bile duct stones (CBDS) that cannot be extracted by endoscopic retrograde cholangiopancreatography (ERCP), management can be safely by open or laparoscopic CBD exploration (CBDE). The study aimed to assess these surgical procedures after endoscopic failure.

          Methods

          We analyzed 85 patients underwent surgical management of difficult CBDS after ERCP failure, in the period from 2013 to 2018.

          Results

          Sixty-seven (78.8%) and 18(21.2%) of our patients underwent single and multiple ERCP sessions respectively. An impacted large stone was the most frequent cause of ERCP failure (60%). Laparoscopic CBDE(LCBDE), open CBDE(OCBDE) and the converted cases were 24.7% (n = 21), 70.6% (n = 60), and 4.7% (n = 4) respectively. Stone clearance rate post LCBDE and OCBDE reached 95.2% and 95% respectively, Eleven (12.9%) of our patients had postoperative complications without mortality. By comparing LCBDE and OCBDE; there was a significant association between the former and longer operative time. On comparing, T-tube and 1ry CBD closure in both OCBDE and LCBDE, there was significantly longer operative time, and post-operative hospital stays in the former. Furthermore, in OCBDE group, choledocoscopy had an independent direction to 1ry CBD repair and significant association with higher stone clearance rate, shorter operative time, and post-operative hospital stay.

          Conclusion

          Large difficult CBDS can be managed either by open surgery or laparoscopically with acceptable comparable outcomes with no need for multiple ERCP sessions due to their related morbidities; furthermore, Open choledocoscopy has a good impact on stone clearance rate with direction towards doing primary repair that is better than T-tube regarding operative time and post-operative hospital stay.

          Highlights

          • Large difficult CBD stones can be managed either by open surgery or laparoscopically with acceptable comparable outcomes.

          • No need for multiple ERCP sessions due to their related morbidities.

          • Open choledocoscopy has a good impact on stone clearance rate with direction towards doing primary repair.

          • Primary repair is better than T-tube regarding operative time and post-operative hospital stay.

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          Most cited references86

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          Adverse events associated with ERCP.

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            Guidelines on the management of common bile duct stones (CBDS).

            The last 30 years have seen major developments in the management of gallstone-related disease, which in the United States alone costs over 6 billion dollars per annum to treat. Endoscopic retrograde cholangiopancreatography (ERCP) has become a widely available and routine procedure, whilst open cholecystectomy has largely been replaced by a laparoscopic approach, which may or may not include laparoscopic exploration of the common bile duct (LCBDE). In addition, new imaging techniques such as magnetic resonance cholangiography (MR) and endoscopic ultrasound (EUS) offer the opportunity to accurately visualise the biliary system without instrumentation of the ducts. As a consequence clinicians are now faced with a number of potentially valid options for managing patients with suspected CBDS. It is with this in mind that the following guidelines have been written.
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              Systematic review of intraoperative cholangiography in cholecystectomy.

              Intraoperative cholangiography (IOC) is used to detect choledocholithiasis and identify or prevent bile duct injury. The aim of this study was systematically to review the randomized clinical trials of IOC for these two indications.
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                Author and article information

                Contributors
                Journal
                Ann Med Surg (Lond)
                Ann Med Surg (Lond)
                Annals of Medicine and Surgery
                Elsevier
                2049-0801
                31 May 2019
                July 2019
                31 May 2019
                : 43
                : 52-63
                Affiliations
                [a ]Hepatobiliary Surgery, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt
                [b ]Anaesthesia, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt
                [c ]Hepatology and Endoscopy, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt
                [d ]Intervention Radiology, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt
                Author notes
                []Corresponding author. emadgadsalemaa@ 123456yahoo.com
                Article
                S2049-0801(19)30042-1
                10.1016/j.amsu.2019.05.007
                6556483
                31198552
                4cef400c-e3a1-4222-8950-d1038926c3d0
                © 2019 The Author(s)

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 11 February 2019
                : 18 May 2019
                : 23 May 2019
                Categories
                Original Research

                laparoscopic cbde,open cbde,cbd stones
                laparoscopic cbde, open cbde, cbd stones

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