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Once-weekly fluconazole (150, 300, or 450 mg) in the treatment of distal subungual onychomycosis of the fingernail
Lynn Drake ,
Dennis Babel ,
Daniel M. Stewart ,
Phoebe Rich ,
Mark R. Ling ,
Debra Breneman ,
Richard K. Scher ,
Ann G. Martin ,
David M. Pariser ,
Robert J. Pariser ,
Charles N. Ellis ,
Sewon Kang ,
Harry Irving Katz ,
Charles J. McDonald ,
Jennie Muglia ,
Ronald C. Savin ,
Guy Webster ,
Boni E. Elewski ,
James J. Leyden ,
Alicia D. Bucko ,
Eduardo H. Tschen ,
Jon M. Hanifin ,
Manuel R. Morman ,
Jerome L. Shupack ,
Norman Levine ,
Nicholas J. Lowe ,
Wilma F. Bergfeld ,
Charles Camisa ,
David Stuart Feingold ,
Nellie Konnikov ,
Richard B. Odom ,
Raza Aly ,
Donald L. Greer
June 1998
June 1998
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Abstract
Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes.
Fluconazole is active in vitro against the most common pathogens, penetrates into
the nail bed, and is clinically effective in the treatment of a wide variety of fungal
infections.