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      Optimization of phenolics and flavonoids extraction conditions of Curcuma Zedoaria leaves using response surface methodology

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          Abstract

          This study focused on maximizing the extraction yield of total phenolics and flavonoids from Curcuma Zedoaria leaves as a function of time (80–120 min), temperature (60–80 °C) and ethanol concentration (70–90 v/v%). The data were subjected to response surface methodology (RSM) and the results showed that the polynomial equations for all models were significant, did not show lack of fit, and presented adjusted determination coefficients (R 2) above 99%, proving their suitability for prediction purposes. Using desirability function, the optimum operating conditions to attain a higher extraction of phenolics and flavonoids was found to be 75 °C, 92 min of extraction time and 90:10 of ethanol concentration ratios. Under these optimal conditions, the experimental values for total phenolics and flavonoids of Curcuma zedoaria leaves were 125.75 ± 0.17 mg of gallic acid equivalents and 6.12 ± 0.23 mg quercetin/g of extract, which closely agreed with the predicted values. Besides, in this study, the leaves from Curcuma zedoaria could be considered to have the strong antioxidative ability and can be used in various cosmeceuticals or medicinal applications.

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          Antioxidant Activities, Total Phenolics and Flavonoids Content in Two Varieties of Malaysia Young Ginger ( Zingiber officinale Roscoe)

          Ginger (Zingiber officinale Roscoe) is a well known and widely used herb, especially in Asia, which contains several interesting bioactive constituents and possesses health promoting properties. In this study, the antioxidant activities of methanol extracts from the leaves, stems and rhizomes of two Zingiber officinale varieties (Halia Bentong and Halia Bara) were assessed in an effort to compare and validate the medicinal potential of the subterranean part of the young ginger. The antioxidant activity and phenolic contents of the leaves as determined by the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) assay and the total amounts of phenolics and flavonoids were higher than those of the rhizomes and stems. On the other hand, the ferric reducing/antioxidant potential (FRAP) activity of the rhizomes was higher than that of the leaves. At low concentration the values of the leaves’ inhibition activity in both varieties were significantly higher than or comparable to those of the young rhizomes. Halia Bara had higher antioxidant activities as well as total contents of phenolic and flavonoid in comparison with Halia Bentong. This study validated the medicinal potential of the leaves and young rhizome of Zingiber officinale (Halia Bara) and the positive relationship between total phenolics content and antioxidant activities in Zingiber officinale.
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            Oxygen radical absorbance capacities of grape/wine industry byproducts and effect of solvent type on extraction of grape seed polyphenols

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              Optimization of ultrasonic extraction of phenolic compounds from Euryale ferox seed shells using response surface methodology

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                Author and article information

                Contributors
                fauwizah_nur@yahoo.com
                +603 89468431 , ssalwaag@upm.edu.my , ssalwa.abdgani@gmail.com
                nor_fadzillah@upm.edu.my
                Journal
                Chem Cent J
                Chem Cent J
                Chemistry Central Journal
                Springer International Publishing (Cham )
                1752-153X
                2 October 2017
                2 October 2017
                2017
                : 11
                : 96
                Affiliations
                [1 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Department of Agriculture Technology, Faculty of Agriculture, , Universiti Putra Malaysia (UPM), ; 43400 Serdang, Selangor Malaysia
                [2 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Halal Products Research Institute, , Universiti Putra Malaysia (UPM), ; 43400 Serdang, Selangor Malaysia
                [3 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Institute for Mathematical Research (INSPEM), , Universiti Putra Malaysia (UPM), ; 43400 Serdang, Selangor Malaysia
                Article
                324
                10.1186/s13065-017-0324-y
                5624860
                29086882
                4ed3879b-a2da-4654-93bc-7301336ceec3
                © The Author(s) 2017

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 24 August 2016
                : 21 September 2017
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100004530, Universiti Putra Malaysia;
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2017

                Chemistry
                curcuma zedoaria,antioxidant activity,response surface methodology,phenolic,flavonoids
                Chemistry
                curcuma zedoaria, antioxidant activity, response surface methodology, phenolic, flavonoids

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